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Paper
Title

Evaluation of antibiotic resistance pattern of Acinetobacter strains isolated from patients admitted to four hospitals in Isfahan province

Year: 1400
COI: MEDISM22_364
Language: EnglishView: 45
نسخه کامل این Paper ارائه نشده است و در دسترس نمی باشد

Authors

Zahra Abbasi - Department of Biotechnology, Faculty of Biological Sciences and Technology, Shahid Ashrafi Esfahani University
Dariush Shokri - Department of Biotechnology, Faculty of Biological Sciences and Technology, Shahid Ashrafi Esfahani University
Seyyed Mahdi Ghasemi - Department of Biotechnology, Faculty of Biological Sciences and Technology, Shahid Ashrafi Esfahani University

Abstract:

Background and Aim : Nosocomial infections are common causes of mortality, disability, increased length of hospital stay, increased hospital costs, and health problems. . Although efforts to control nosocomial infections have been successful, recent advances in medical science and repeated medical interventions, including the widespread use of immunosuppressive and anti-inflammatory drugs, have been successful. Antibiotics have increased the number of vulnerable people, which has been exacerbated by the development of transmissible resistance to pathogens against antibiotics. . Multidrug resistance to gram-negative bacteria such as Acinetobacter is a growing global problem. The aim of this study was to evaluate the pattern of antibiotic resistance of Acinetobacter strains isolated from patients admitted to four main hospitals in Isfahan province.Methods : In this study, during six months, ۵۳ strains of Acinetobacter were collected from four main hospitals in Isfahan province. Biochemical tests were performed to identify the isolated bacteria. Antibiotic susceptibility testing was performed by disk diffusion method.Results : The results of antibiotic susceptibility test showed that the highest susceptibility of ۴۶ strains (۸۷%) was to colistin antibiotic and ۵۳ strains (۱۰۰%) were resistant to meropenem, ciprofloxacin and piperacillin tazobactam. Other antibiotics include: ۵۲ strains of ceftazidime (۹۸.۱%) resistant and ۱ strain (۱.۹%) semi-sensitive, gentamicin ۵۰ strains (۹۴.۳%) resistant and ۱ strain (۱.۹%) semi-sensitive and ۲ Sensitive strain (۳.۷%), cefipime ۴۷ strains (۸۸.۶۸%) resistant and ۶ strains (۱۱.۳۲%) semi-susceptible, trimenoprim sulfamethoxazole ۴۷ strains (۸۸.۶۸%) resistant and ۳ strains (۵.۶%) semi-sensitive and ۳ strains (۵.۶%) sensitive, ampicillin sulbactam ۴۶ strains (۸۶.۸۰%) resistant and ۶ strains (۱۱.۳۲%) semi-sensitive and ۱ strain (۱.۹%) sensitive, amikacin ۴۵ strains (۸۴.۹۰%) resistant And ۳ strains (۵.۶%) are semi-sensitive and ۵ strains are sensitive (۹.۴۳%). Conclusion : Antibiotic susceptibility testing of Acinetobacter strains showed that ۶ strains of MDR (Multidrug resistant), ۴۳ strains of XDR (Extensively drug resistant) and ۴ strains of PDR (Pandrug resistant) were detected. Since Acinetobacter is one of the most important causes of nosocomial infections, it is necessary to study the patterns of drug resistance in it.

Keywords:

Paper COI Code

This Paper COI Code is MEDISM22_364. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1279222/

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If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Abbasi, Zahra and Shokri, Dariush and Ghasemi, Seyyed Mahdi,1400,Evaluation of antibiotic resistance pattern of Acinetobacter strains isolated from patients admitted to four hospitals in Isfahan province,Twenty-second Iranian Congress of Microbiology (Virtual),https://civilica.com/doc/1279222

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Type of center: موسسه غیرانتفاعی
Paper count: 545
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