COVID-۱۹ Mimicking Hemolysis, Elevated Liver Enzymes and Low Platelets (HELLP) Syndrome: A Case Report

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JMREH-9-4_013

تاریخ نمایه سازی: 11 مهر 1400

Abstract:

Background & aim: Hemolysis, elevated liver enzymes, and low platelets syndrome (HELLP) was mimicked by several infectious conditions. It is critically important to distinguish these two, since their management and course differs, substantially.Case report: The case was a ۲۷-year-old gravid patient with gestational age of ۳۰ weeks who initially presented with headache and lower limb pain as well as leukopenia (and lymphopenia), normochromic normocytic anemia, thrombocytopenia, abnormal liver enzymes, increased lactate dehydrogenase enzyme and C-reactive protein. The patient was initially managed for HELLP syndrome, but due to the atypical presentation (low blood pressure and an episode of delirium when admitted), the novel coronavirus disease ۲۰۱۹ (COVID-۱۹), real-time reverse transcription polymerase chain reaction (rRT-PCR) was requested for the patient that was positive. The spiral lung high-resolution computed tomography scan revealed changes compatible with COVID-۱۹ diagnosis. Finally, the patient underwent uncomplicated normal vaginal delivery at ۳۹th gestational week.Conclusion: It is important to consider the COVID-۱۹ in differential diagnosis of patients suspected to HELLP syndrome, as the isolation and treatment of the patient is different and time-sensitive.

Authors

Helena Azimi

Assistant Professor, Fellowship of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Nafiseh Saghafi

Associate professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Fatemeh Tara

Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Sara Mirzaeian

Assistant professor, Department of Obstetrics and Gynecology, Fellowship of Perinatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Zahra Hatamian

Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Farzaneh Afshar Delkhah

Resident, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

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