Identification of Key Proteins in different stages of Hepatocellular carcinoma (HCC) compared to Normal Liver tissue with a Systems Biology approach

Liver cancer is the sixth most common cancer worldwide, among different liver malignancies, hepatocellular carcinoma (HCC) is the most prevalent. Bad prognosis and increasing incidence rate of liver cancer leads to extensive studies on it.in this study with a holistic look to associated proteins in liver cancer in a network and utilizing bioinformatics tools to analyze them, key proteins of this disease that can be use as therapeutic or diagnostic targets, have been identified with a systems biology approach

Keywords:

Liver cancer , hepatocellular carcinoma , systems biology , biological network , bioinformatics