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Title

Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review

Year: 1396
COI: JR_IJBMS-20-6_001
Language: EnglishView: 46
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Authors

Fatemeh Ayoobi - Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Ali Shamsizadeh - Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Iman Fatemi - Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Alireza Vakilian - Geriatric Care Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Mohammad Allahtavakoli - Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Gholamhossein Hassanshahi - Pistachio Safety Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Amir Moghadam-Ahmadi - Department of Neurology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

Abstract:

The Achillea millefolium L. (Yarrow) is a common herb which is widely being used, worldwide. Achillea is being used for treatment of many disorders since centuries. It is considered safe for supplemental use and flavonoids such as kaempferol, luteolin and apigenin are of main constituents present in Achillea. Most of both antioxidant and anti-inflammatory properties of this herb have been attributed to its flavonoid content. Oxidative and inflammatory processes play important roles in pathogenesis of neurodegenerative diseases. Present review was aimed to review the latest literature evidences regarding application of Achillea and/or its three main flavonoid constituents on epilepsy, Alzheimer's disease, multiple sclerosis, Parkinson's disease and stroke.

Keywords:

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This Paper COI Code is JR_IJBMS-20-6_001. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1295704/

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Ayoobi, Fatemeh and Shamsizadeh, Ali and Fatemi, Iman and Vakilian, Alireza and Allahtavakoli, Mohammad and Hassanshahi, Gholamhossein and Moghadam-Ahmadi, Amir,1396,Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review,https://civilica.com/doc/1295704

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