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Maggot Debridement Therapy (MDT) for Treatment of Cutaneous Leishmaniasis Wound using Lucilia serricata Larvae in Iran: Case Reports

عنوان مقاله: Maggot Debridement Therapy (MDT) for Treatment of Cutaneous Leishmaniasis Wound using Lucilia serricata Larvae in Iran: Case Reports
شناسه ملی مقاله: JR_ZUMS-30-13838_001
منتشر شده در در سال 1400
مشخصات نویسندگان مقاله:

Asghar Nasiri - Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Elham Jahanifard - Dept. of Medical Entomology and Vector Control, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Mona Sharififard - Dept. of Medical Entomology and Vector Control, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Reza Arjmand - Dept. of Medical Parasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Sima Rasai - Dept. of Dermatology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Tahmaseb Haeri - Health Center of Andimeshk County, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

خلاصه مقاله:
Article Number: e۵۶۶۴۱ Leishmaniasis is a worldwide vector-borne disease. The Cutaneous form of this disease leaves chronic wounds on the patientchr('۳۹')s skin. The purpose of this study was to treat cutaneous leishmaniasis woundsusing Lucilia serricata larvae. Leishman’s body was confirmed and Leishmania major was identified using PCR test in the samples of three patients in health center of Andimeshk County, southwest Iran during ۲۰۱۹-۲۰۲۰. The patients signed an informed consent form to receive maggot therapy. Five to ten sterile ۱st instar larva of L. serricata per cm۲ wound were inserted directly on the wounds in ۴۸-hours intervals and bandaged with sterile saline gauze. Cutaneous leishmaniasis wounds were free of purulent secretion within ۹-۱۲ days. After ۳۰- ۴۵ days of treatment; the wounds were healed entirely without leaving scar tissues. The results showed larvae of L. sericata can significantly improve wound healing rate but it is recommended to evaluate this biotherapy method in more patients.

کلمات کلیدی:
Maggot, Biotherapy, Cutaneous Leishmanisis

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1296127/