The Effect of Sun Radiation on the Course of Cutaneous Leishmaniasis in BALB/c Mice

Publish Year: 1390
نوع سند: مقاله ژورنالی
زبان: English
View: 115

This Paper With 6 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_IJBMS-14-2_007

تاریخ نمایه سازی: 3 آبان 1400

Abstract:

Objective(s) Studies have described immunomedulatory effects of sun exposure and ultraviolet radiation on infectious and neoplastic diseases. Here the effect of exposure to low potency radiation of sun on the course of leishmaniasis in mice was studied. Materials and Methods Fifteen BALB/c mice were exposed to suberythemogenic doses of sun (mean ۱۸۰ mJ/cm۲/day of UVB) ۲ months before and ۴ months after Leishmania major inoculation to food pad. Control group was kept in the sun protected environment. From ۲nd to ۱۷th week after inoculation, size of the lesion was recorded in each group weekly and at last week the parasite burden in spleen was detected. Results were compared between two groups. Results Seven mice from case group and ۹ mice from control group survived up to last week. The mean lesion size was ۰.۹۰±۰.۵۹ cm in exposed and ۴.۰۱±۳.۵۹ cm in unexposed mice (P= ۰.۰۳۷). Parasite burden in spleen of case and control groups were ۵.۵±۴.۶۱ and ۱۰۶.۹۴±۲۷۹.۷۶ respectively (P= ۰.۰۰۶). Conclusion Chronic exposure of BALB/c mice to suberythemogenic doses of sun suppressed skin lesion and decreased the extension of L. major to spleen.

Authors

Fateme Hoseinipoor

Department of Dermatology, Emamreza Hospital, Mashhad, Iran

Mahnaz Banihashemi

Department of Dermatology, Gaem Hospital, Mashhad, Iran

Mohammad Reza Jaafari

Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Zari Javidi

Department of Dermatology, Emamreza Hospital, Mashhad, Iran

Amir Abas Azarian

Mashhad University of Medical Sciences, Mashhad, Iran

Vahid Mashayekhi Goyonlo

Department of Dermatology, Emamreza Hospital, Mashhad, Iran

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • Ardehali SD, Rezaee HR, Nadim AH. Leishmaniasis and Leishmania parasite. ...
  • Kemp M, Hey AS, Kurtzhals JA, Christensen CB, Gaafar A, ...
  • Lopez, FV, Hay RJ. Parasitic worms and protozoa. In: Burns ...
  • Ghosn S, Kurban A. Leishmaniasis and other protozoan in infections. ...
  • Hawk JLM, Young AR, Ferguson J. Cutaneous Photobiology. In: Burns ...
  • Musa AM, Khalil EA, Raheem MA, Zijlstra EE, Ibrahim ME, ...
  • Ismail A, Khalil EA, Musa AM, El Hassan IM, Ibrahim ...
  • Khaskhely NM, Maruno M, Uezato H, Takamiyagi A, Ramzi ST, ...
  • Jaafari MR, Bavarsad N, Fazly Bazzaz A, Samiei A, Soroush ...
  • Jaafari MR, Ghafarian A, Farrokh-Gisour A, Samiei A, Kheiri MT, ...
  • Brown EL, Rivas JM, Ullrich SE, Young CR,Norris SJ, Kripke ...
  • Denkins Y, Fidler IJ, Kripke ML. Exposure of mice to ...
  • Howie S, Norval M, Maingay J. Exposure to low-dose ultraviolet ...
  • Jeevan A, Kripke ML. Effect of a single exposure to ...
  • Jeevan A, Gilliam K, Heard H, Kripke ML. Effects of ...
  • Noonan FP, Alewis FA. UVB- induced immune suppression and infection ...
  • Garssen J, Vandebriel RJ, De Gruijl FR, Wolvers DA, Van ...
  • Reiner SL, Locksley RM. The regulation of immunity to Leishrmania ...
  • Abbas AK, Murphy KM, Sher A. Functional diversity of helper ...
  • Louis J, Himmelrich H, Parra-Lopez C, Tacchini-Cottier F, Launois P.Regulation ...
  • Schade N, Esser C, Krutmann J. Ultraviolet B radiation-induced immunosuppression: ...
  • Schwarz T. Mechanisms of UV-induced immunosuppression. Keio J Med ۲۰۰۵; ...
  • Sleijffers A, Garssen J, Vos JG, Loveren H. Ultraviolet light ...
  • Narbutt J, Lesiak A, Sysa-Jedrzejowska A, Wozniacka A, Cierniewska-Cieslak A, ...
  • McLoone P, Norval M. Adaptation to the UV-induced suppression of ...
  • Giannini MS. Suppression of pathogenesis in cutaneous leishmaniasis by UV ...
  • Khaskhely NM, Maruno M, Takamiyagi A, Uezato H, Kasem KM, ...
  • Kricker A, Armstrong BK, English DR, Heenan PJ. A dose- ...
  • Kricker A, Armstrong BK, English DR, Heenan PJ. Dose intermittent ...
  • Lee JAH. Melanoma and exposure to sunlight. Epidermol Rev ۱۹۸۲; ...
  • Osterlind A, Tucker MA, Stone BJ, Jensen OM. The Danish ...
  • نمایش کامل مراجع