Cardio-protective and anti-cancer therapeutic potential of Nigella sativa

Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
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JR_IJBMS-17-12_006

تاریخ نمایه سازی: 4 آبان 1400

Abstract:

Nigella sativa is the miraculous plant having a lot of nutritional and medicinal benefits, and attracts large number of nutrition and pharmacological researchers. N. sativa seed composition shows that it is the blessing of nature and it contains and many bioactive compounds like thymoquinone, α-hederin, alkaloids, flavonoids, antioxidants, fatty acids many other compounds that have positive effects on curing of different diseases. Several medicinal properties of N. sativa like its anti-cancer, anti-inflammatory, anti-diabetic, antioxidant activities and many others are well acknowledged. However, this article focuses on activity of N. sativa against cardiovascular diseases and cancer. For gathering required data the authors went through vast number of articles using search engines like Science direct, ELSEVIER, Pub Med, Willey on Line Library and Google scholar and the findings were classified on the basis of relevance of the topic and were reviewed in the article. N. sativa is rich source of different biologically active compounds and is found effective in controlling number of cardiovascular diseases and various cancers both in vivo and in vitro studies.

Authors

Hammad Shafiq

Department of Food Technology, PMAS Arid Agriculture University Rawalpindi, ۴۳۶۰۰ Pakistan

Asif Ahmad

Department of Food Technology, PMAS Arid Agriculture University Rawalpindi, ۴۳۶۰۰ Pakistan Corn, Soybean and Wheat Quality Labs., ۲۰۵ Williams Hall, ۱۶۸۰ Madison Avenue, Wooster, OH ۴۴۶۹۱ USA

Tariq Masud

Department of Food Technology, PMAS Arid Agriculture University Rawalpindi, ۴۳۶۰۰ Pakistan

Muhammad Kaleem

Department of Food Technology, PMAS Arid Agriculture University Rawalpindi, ۴۳۶۰۰ Pakistan

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  • Paarakh PM. Nigella sativa Linn.–A comprehensive review. Indian J Natu ...
  • Grover J, Yadav S. Pharmacological actions and potential uses of ...
  • Mills S, Bone K. Principles and practice of phytotherapy. Modern ...
  • Ahmad A, Husain A, Mujeeb M, Khan SA, Najmi AK, ...
  • Al-Khalaf MI, Ramadan KS. Antimicrobial and Anti-cancer Activity of Nigella ...
  • Ismail MYM. Therapeutic Role of Prophetic Medicine Habbat El Baraka ...
  • Gilani A, Jabeen Q, Khan M. A review of medicinal ...
  • Zohary D, Hopf M, Weiss E. Domestication of Plants in ...
  • Sharma NK, Ahirwar D, Jhade D, Gupta S. Medicinal and ...
  • Randhawa MA, Alghamdi MS. Anti-cancer activity of Nigella sativa (black ...
  • Nasir A, Siddiqui MY, Mohsin M. Therapeutic Uses of Shoneez ...
  • Al-Bukhari MI, Sahih Al-Bukhari. The Collection of Authentic Sayings of ...
  • Alwan A. Global status report on noncommunicable diseases ۲۰۱۰: World ...
  • WHO. Cardiovascular diseases ۲۰۱۳ [۲۵/۴/۲۰۱۴]. Available from: http://www.-who.int/diabetes/facts/en/ ...
  • Mathers CD, Loncar D. Projections of global mortality and burden ...
  • WHO. Cancer fact sheet ۲۰۱۳ [۲۵/۴/۲۰۱۴]. Available from: http://www.who.int/ mediacentre/-factsheets/ ...
  • Reuters T. Cancer cases worldwide likely to rise to ۲۲ ...
  • Warrier P, Nambiar V, Ramankutty C. Indian medicinal plants: a ...
  • Yarnell E, Abascal K. Nigella sativa: holy herb of the ...
  • Ramadan MF. Nutritional value, functional properties and nutraceutical applications of ...
  • Goreja WC. Black seed: nature's miracle remedy: TNC International Inc; ...
  • Padhye S, Banerjee S, Ahmad A, Mohammad R, Sarkar FH. ...
  • Sharma P, Yelne M, Dennis T, Joshi A, Billore K. ...
  • Chakravarty N. Inhibition of histamine release from mast cells by ...
  • Ali B, Blunden G. Pharmacological and toxicological properties of Nigella ...
  • Khan M, Ashfaq M, Zuberi H, Mahmood M, Gilani A. ...
  • Al-Ghamdi M. The anti-inflammatory, analgesic and antipyretic activity of Nigella ...
  • Khan MA, Chen HC, Tania M, Zhang DZ. Anti-cancer activities ...
  • Nergiz C, Ötleş S. Chemical composition of Nigella sativa L. ...
  • Khan MA. Chemical composition and medicinal properties of Nigella sativa ...
  • Nickavar B, Mojab F, Javidnia K, Amoli MR. Chemical composition ...
  • Cheikh-Rouhou S, Besbes S, Hentati B, Blecker C, Deroanne C, ...
  • Yusuf S, Reddy S, Ôunpuu S, Anand S. Global burden ...
  • Mendis S, Puska P, Norrving B. Global atlas on cardiovascular ...
  • Sabzghabaee AM, Dianatkhah M, Sarrafzadegan N, Asgary S, Ghannadi A. ...
  • El-Dakhakhny M, Mady NI, Halim MA. Nigella sativa L. oil ...
  • Amarouch H, Zaoui A, Cherrah Y, Alaoui K, Mahassini N, ...
  • Al-Naqeep G, Al-Zubairi AS, Ismail M, Amom ZH, Esa NM. ...
  • Nader MA, El-Agamy DS, Suddek GM. Protective effects of propolis ...
  • Le PM, Benhaddou-Andaloussi A, Elimadi A, Settaf A, Cherrah Y, ...
  • Zaoui A, Cherrah Y, Alaoui K, Mahassine N, Amarouch H, ...
  • Bhatti IU, Rehman FU, Khan M, Marwat S. Effect of ...
  • Tasawar Z, Siraj Z, Ahmad N, Lashari MH. The effects ...
  • Bamosa AO, Ali B, Sowayan S. Effect of oral ingestion ...
  • Bamosa AO, Ali BA, al-Hawsawi ZA. The effect of thymoquinone ...
  • Kanter M, Coskun O, Budancamanak M. Hepatoprotective effects of Nigella ...
  • Sowers JR, Epstein M. Diabetes mellitus and associated hypertension, vascular ...
  • Daneman D. Type ۱ diabetes. The Lancet ۲۰۰۶; ۳۶۷:۸۴۷-۸۵۸ ...
  • Anonymous. Guidelines N. Anaemia management in people with chronic kidney disease (CKD). Clinical ...
  • Stadler K. Oxidative stress in diabetes. Adv Exp Med Biol ...
  • Shabana A, El-Menyar A, Asim M, Al-Azzeh H, Al Thani ...
  • Kanter M, Akpolat M, Aktas C. Protective effects of the ...
  • Abdelmeguid NE, Fakhoury R, Kamal SM, Al Wafai RJ. Effects ...
  • Kanter M, Coskun O, Korkmaz A, Oter S. Effects of ...
  • Rchid H, Chevassus H, Nmila R, Guiral C, Petit P, ...
  • Al-Hader A, Aqel M, Hasan Z. Hypoglycemic effects of the ...
  • Fararh K, Atoji Y, Shimizu Y, Takewaki T. Isulinotropic properties ...
  • Kaleem M, Kirmani D, Asif M, Ahmed Q, Bano B. ...
  • Alenzi F, El-Bolkiny Y-S, Salem M. Protective effects of Nigella ...
  • Hawsawi ZA, Ali BA, Bamosa AO. Effect of Nigella sativa ...
  • Marles RJ, Farnsworth NR. Antidiabetic plants and their active constituents. ...
  • Abu Khader MM. Thymoquinone: a promising antidiabetic agent. Int J ...
  • Salama RH. Hypoglycemic effect of lipoic acid, carnitine and Nigella ...
  • Pari L, Sankaranarayanan C. Beneficial effects of thymoquinone on hepatic ...
  • Bamosa AO, Kaatabi H, Lebda FM, Elq A-MA, Al-Sultan A. ...
  • Sultan MT, Butt MS, Karim R, Zia-Ul-Haq M, Batool R, ...
  • Ibrahim RM, Hamdan NS, Mahmud R, Imam MU, Saini SM, ...
  • Sheikh T, Joshi D, Patel B, Modi C. Protective role ...
  • Alam S, Reddy SK, Baig A, Reddy MK, Mohiuddin M, ...
  • Asgary S, Ghannadi A, Dashti G, Helalat A, Sahebkar A, ...
  • Ali SA, Asghar F, Nafees M, Tayyab M. Effect of ...
  • Nasir A, Siddiqui MY, Mohsin M. Efficacy of Saboos-e-Asapghol (Plantago ...
  • Mahmoud MY. Effect of High Protein Diet Containing Fortified Bread ...
  • Shafeeque A. Effects of volatile oil and nonsaponifiable fractions from ...
  • Alimohammadi S, Hobbenaghi R, Javanbakht J, Kheradmand D, Mortezaee R, ...
  • Sobhi W, Khettal B, Belmouhoub M, Atmani D, Duez P, ...
  • Jamal A, Hmza A, Omar E, Adnan A, Osman MT. ...
  • Vanhoutte P, Shimokawa H, Tang E, Feletou M. Endothelial dysfunction ...
  • Idris-Khodja N, Schini-Kerth V. Thymoquinone improves aging-related endothelial dysfunction in ...
  • Zaoui A, Cherrah Y, Lacaille-Dubois M, Settaf A, Amarouch H, ...
  • Demir H, Kanter M, Coskun O, Uz YH, Koc A, ...
  • El Tahir KE, Ashour MM, Al-Harbi MM. The cardiovascular actions ...
  • Khattab MM, Nagi MN. Thymoquinone supplementation attenuates hypertension and renal ...
  • Meral I, Donmez N, Baydas B, Belge F, Kanter M. ...
  • Dehkordi FR, Kamkhah AF. Antihypertensive effect of Nigella sativa seed ...
  • Qidwai W, Hamza HB, Qureshi R, Gilani A. Effectiveness, safety, ...
  • American Cancer Society. Cancer Facts and Statistics ۲۰۱۴ [۲۵/۴/۲۰۱۴]. Avalible ...
  • Wang S, Meckling KA, Marcone MF, Kakuda Y, Tsao R. ...
  • Wargovich MJ. Anti-cancer properties of fruits and vegetables. HortSci ۲۰۰۰; ...
  • Ait Mbarek L, Ait Mouse H, Elabbadi N, Bensalah M, ...
  • Gali-Muhtasib H, Roessner A, Schneider-Stock R. Thymoquinone: a promising anti-cancer ...
  • Rooney S, Ryan M. Effects of alpha-hederin and thymoquinone, constituents ...
  • Al-Ali A, Alkhawajah AA, Randhawa MA, Shaikh NA. Oral and ...
  • El-Kadi A, Kandil O, editors. Effects of Nigella sativa (the ...
  • Mabrouk GM, Moselhy SS, Zohny SF, Ali EM, Helal TE, Amin AA, et al. Inhibition ...
  • Swamy S, Tan B. Cytotoxic and immunopotentiating effects of ethanolic ...
  • Kumara SS, Huat BT. Extraction, isolation and characterisation of antitumor ...
  • Jafri SH, Glass J, Shi R, Zhang S, Prince M, ...
  • Bourgou S, Pichette A, Marzouk B, Legault J. Bioactivities of ...
  • Al-Sheddi ES, Farshori NN, Al-Oqail MM, Musarrat J, Al-Khedhairy AA, ...
  • Globocan. Fact sheet [۲۷/۴/۲۰۱۴]. Available from: http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx ...
  • Farah IO, Begum RA. Effect of Nigella sativa (N. sativa ...
  • Farah IO. Assessment of cellular responses to oxidative stress using ...
  • El‐Aziz MA, Hassan HA, Mohamed MH, Meki AR, Abdel‐Ghaffar SK, ...
  • Effenberger K, Breyer S, Schobert R. Terpene Conjugates of the ...
  • Baharetha HM, Nassar ZD, Aisha AF, Ahamed MB, Al-Suede FS, ...
  • Salim EI, Fukushima S. Chemopreventive potential of volatile oil from ...
  • Gali-Muhtasib H, Diab-Assaf M, Boltze C, Al-Hmaira J, Hartig R, ...
  • ۱۱۰. Rooney S, Ryan M. Modes of action of alpha-hederin and ...
  • Khan N, Sultana S. Inhibition of two stage renal carcinogenesis, ...
  • Tabasi N, Mahmoudi M, Rastin M, Sadeghnia HR, HosseinPour Mashhadi ...
  • Iddamaldeniya SS, Wickramasinghe N, Thabrew I, Ratnatunge N, Thammitiyagodage MG. ...
  • Iddamaldeniya SS, Thabrew M, Wickramasinghe S, Ratnatunge N, Thammitiyagodage MG. ...
  • Thabrew MI, Mitry RR, Morsy MA, Hughes RD. Cytotoxic effects ...
  • Samarakoon SR, Thabrew I, Galhena PB, De Silva D, Tennekoon ...
  • Salomi MJ, Nair SC, Panikkar KR. Inhibitory effects of Nigella ...
  • Chehl N, Chipitsyna G, Gong Q, Yeo CJ, Arafat HA. ...
  • Banerjee S, Kaseb AO, Wang Z, Kong D, Mohammad M, ...
  • Torres MP, Ponnusamy MP, Chakraborty S, Smith LM, Das S, ...
  • Shafi G, Munshi A, Hasan TN, Alshatwi AA, Jyothy A, ...
  • Hasan TN, Shafi G, Syed NA, Alfawaz MA, Alsaif MA, ...
  • Salomi N, Nair S, Jayawardhanan K, Varghese C, Panikkar K. ...
  • Worthen DR, Ghosheh OA, Crooks P. The in vitro anti-tumor ...
  • Badary O, AI-Shabanah O, Nagi M, AI-Rikabi A, Elmazar M. ...
  • Badary OA, El-Din AMG. Inhibitory effects of thymoquinone against ۲۰-methylcholanthrene-induced ...
  • Norwood A, Tucci M, Benghuzzi H. A comparison of ۵-fluorouracil ...
  • Norwood A, Tan M, May M, Tucci M, Benghuzzi H. ...
  • El‐Mahdy MA, Zhu Q, Wang QE, Wani G, Wani AA. ...
  • Ahmed WA, Hassan SA, Galeb FM, El-Taweel MA, Abu-Bedair FA. ...
  • Hassan S, Ahmed W, M.Galeb F, El-Taweel M, A.Abu-Bedair f. ...
  • El-Najjar N, Chatila M, Moukadem H, Vuorela H, Ocker M, ...
  • Salomi M, Nair SC, Panikkar K. Inhibitory effects of Nigella ...
  • Kaseb AO, Chinnakannu K, Chen D, Sivanandam A, Tejwani S, ...
  • Koka PS, Mondal D, Schultz M, Abdel-Mageed AB, Agrawal KC. ...
  • Yi T, Cho S-G, Yi Z, Pang X, Rodriguez M, ...
  • Xuan NT, Shumilina E, Qadri SM, Goetz F, Lang F. ...
  • Sethi G, Ahn KS, Aggarwal BB. Targeting nuclear factor-κB activation ...
  • Ismail M, Al-Naqeep G, Chan KW. Nigella sativa thymoquinone-rich fraction ...
  • Ebru U, Burak U, Yusuf S, Reyhan B, Arif K, ...
  • Barron J, Benghuzzi H, Tucci M. Effects of thymoquinone and ...
  • Bawadi H. A, Bansode R. R, Losso J. N. Thymoquinone ...
  • نمایش کامل مراجع