Parvin Bastani - Department of gynecology, Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Malahat Ebrahimpour - Department of gynecology, Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Fatemeh Mallah - Department of gynecology, Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Sakineh Hajebrahimi - Research Center for Evidence-Based Medicine, Iranian EBM Center: A Joanna Briggs Institute Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran
Hanieh Salehi Pourmehr - Research Center for Evidence-Based Medicine, Iranian EBM Center: A Joanna Briggs Institute Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran

Background & Objective: Pelvic organ prolapse (POP) is accompanied by a remarkable decline in the quality of life. Determining the best surgical approach for women with POP is difficult because of outcome variations. We compared the outcomes of pelvic organ prolapse (POP) treatment by abdominal sacrocolpopexy (ASC) and vaginal sacrospinous ligament suspension (SSLS) for advanced apical prolapse beyond the level of the hymen (stage≥ II).  Materials & Methods: This retrospective study was conducted on a case series of ۵۸ ASC and ۴۸ SSLS surgeries, which were performed through the posterior approach for advance prolapse during January ۲۰۱۹-April ۲۰۲۰. Pelvic Floor Disability Index (PFDI-۲۰) questionnaire was completed both at the first visit and a year postop. All patients were visited ten days after the procedure and re-visited after ۲, ۴, ۶, and ۱۲ months. Results: Of a total of ۱۰۶ women, ۸۰ cases completed the study (n=۴۰ in each group). Within-group analysis showed that the overall score of PFDI-۲۰ and its subscales decreased in both evaluated groups after surgery (P<۰.۰۰۱). However, the between-group analysis revealed that this reduction in the ASC group was statistically significant in the total score of PFDI, POPDI-۶, and UDI-۶ subscales (P<۰.۰۵). In addition, vaginal length was demonstrated to improve in both groups, which was statistically significant in the ASC group (P=۰.۰۰۱). The stage of prolapse was improved in both groups (P<۰.۰۰۱), and it was more significant in the ASC group (P=۰.۰۴۹). There was no statistically significant difference between the SSLS and ASC in terms of the rate of satisfaction (۹۳% vs. ۱۰۰%; P=۰.۲۴۱). Conclusion: According to our findings, ASC and SSLS diminished the symptoms of POP. The surgery approach should be chosen based on the condition of patients, POP stage, and the experience of surgeons.

Aabdominal Sacrocolpopexy, Apical, Pelvic organ prolapse, Vaginal sacrospinous ligament suspensions