ناشر تخصصی کنفرانس های ایران

لطفا کمی صبر نمایید

Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها
Paper
Title

Effect of metformin on pregnancy outcome in healthy overweight pregnant women; a double-blinded parallel randomized clinical trial

Year: 1400
COI: HSEBCNF04_039
Language: EnglishView: 68
This Paper With 10 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 10 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:

Authors

Shabnam Vazifekhah - Urmia University of Medical Sciences, Urmia, Iran
Samira Esmaieli - Urmia University of Medical Sciences, Urmia, Iran
Javad Rasuoli - Urmia University of Medical Sciences, Urmia, Iran

Abstract:

Introduction: Maternal obesity increases the risk of pregnancy complications such as preeclampsia, postpartum hemorrhage, weight gain at birth and the need for cesarean section. Interventions that can help prevent fetal macrosomia and its adverse metabolic effects during pregnancy seem to help improve the lives of neonate in future.Objectives: Recently, the role of hyperglycemia and insulin resistance has been cited as factors that lead to increased maternal weight gain during pregnancy and fetal macrosomia and gestational diabetes. And in this study, we studied the role of metformin in overweight of mothers.Patients and Methods: ۳۶۰ pregnant women at ۱۲-۱۶ weeks of pregnancy referred to the gynecology clinic of Motahhari hospital in Urmia were randomly assigned to the two groups of ۱۸۰ individuals. The intervention group was given ۱۰۰۰ mg of metformin and the control group was given placebo. Demographic characteristics of patients such as age, gravidity, parity, preterm infant weight, live birth, abortion, previous delivery method, maternal weight, BMI, birth weight, delivery method, blood sugar at birth, hospitalization rate in NICU, gestational age at birth, neonatal hypoglycemia, infant mortality and anomalies were also recorded. The results were analyzed and evaluated with SPSS ۲۱.Results: Out of ۱۸۰ patients, ۱۶۹ patients remained in the intervention group and ۱۷۱ patients remained in the control group. The demographic characteristics of the mothers were the same in the both groups. In the control group, ۱۲ people (۷%) and in the intervention group, ۱۱ people (۶.۵%) had gestational diabetes (P=۰.۸). In the control group, ۱۳ infants (۷.۶%) and in the intervention group, ۱۲ infants (۷.۱%) had a birth weight more than ۴,۰۰۰ g (P=۰.۸). In the control group, ۱۳ patients (۷.۶%) and in the intervention group, ۵ patients (۲.۹%) had maternal preeclampsia and increased blood pressure during pregnancy (P= ۰.۰۵۳). In the control group, the mean weighting of mothers was ۱۰.۲۲ ± ۳.۳ kg and in the intervention group were ۷.۶ ± ۲.۳ kg during pregnancy (P <۰.۰۰۱).Conclusion: The use of metformin has been shown to be effective in controlling overweight in overweight mothers, but has not affected the birth weight of infants. Metformin has not had an effect on pregnancy results.

Keywords:

Paper COI Code

This Paper COI Code is HSEBCNF04_039. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1302591/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Vazifekhah, Shabnam and Esmaieli, Samira and Rasuoli, Javad,1400,Effect of metformin on pregnancy outcome in healthy overweight pregnant women; a double-blinded parallel randomized clinical trial,Fourth National Conference on Safety and Health,Tehran,https://civilica.com/doc/1302591

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.

Scientometrics

The specifications of the publisher center of this Paper are as follows:
Type of center: دانشگاه دولتی
Paper count: 14,059
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

New Papers

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.

Support