Reference Values for Serum Lipid Profiles in Iranian Adults: A Spline-Based Quantile Regression Method
Publish place: Journal of Nutrition and Food Security، Vol: 6، Issue: 4
Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JNFS-6-4_012
تاریخ نمایه سازی: 15 آبان 1400
Abstract:
Background: Reference measurements are used to screen for abnormal blood lipids. The problem is that these reference values obtained in one population cannot be effective for another population. This study aimed to determine the reference values for blood lipids profiles in the population aged ۲۵-۶۴ years in Yazd. Methods: This descriptive study was based on the data of Yazd Health Study (YaHS) on ۳۸۰۰ adults by cluster sampling. The data set included gender, age, total cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol (LDL-C), and high-density lipoprotein-cholesterol (HDL-C). The linear percentile regression model and the generalized additive model for location, scale, and shape (GAMLSS) were fitted to the data and the reference values were predicted according to the regression coefficients. R-۳.۰.۱ software was used for data analysis. Results: Refrence values for TC, LDL-C, and HDL-C were ۱۰۹.۴۳-۲۷۵.۷۲, ۴۵.۵۸-۱۷۷.۷۰, and ۲۹.۹۵-۶۲.۲۲ mg/dl. The trend of TC, TG, and LDL-C levels increased with age in both genders, but the trend of HDL-C in men decreased with age and remained almost constant in women. Conclusion: In this study, for the population of Yazd, reference values for blood lipids were different in both genders and age groups. Reference values for lipid profile increased in men and women with age.These findings can be used in both prevention and clinical decisions.
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Authors
Hossein Fallahzadeh
Center for Healthcare Data Modeling, School of Public Pealth, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Mahdieh Momayyezi
Deptartment of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Masoud Mirzaei
Center for Healthcare Data Modeling, School of Public Pealth, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
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