The Evaluation of Left Atrial to Aortic Root Diameter Ratio after PDA Closure in Children

Background: Ductus arteriosus (DA) is a vascular structure that makes a link between the proximal descending aorta and main pulmonary artery near the origin of the left pulmonary artery. The present study aimed to assess the changes of LA/Ao ratio after PDA closure in children.Methods: This cross-sectional study was performed on ۶۳۵ children with PDA in the Ali Asghar clinic, Zahedan, Iran, from ۲۰۰۳ to ۲۰۱۹. The participants were followed for at least one year after discharge from the hospital after intervention. PDA diagnosis was conducted in accordance with the echocardiography performed by a pediatric cardiologist using Mylab ۶۰ and challenged ۷۰۰۰ made in Italy.  The analyses were performed by SPSS ۲۰.۰۰, considering ۰.۰۵ as the significant error.Results: As compared to the baseline measures before the interventions, the growth rates of LA/Ao ratio decreased by ۲۴% and ۱۰% in the first and second ۶ months after the intervention. During the first ۶ months after the intervention, the percentages of LA/Ao ratio reduction were ۲۳%, ۲۵% and ۲۲% in small, medium and large PDA while these percentages were ۷%, ۱۳% and ۱۶%   during the second ۶ months after the intervention, respectively. Regarding the intervention, the percentages were ۲۵%, ۲۴%, ۲۴% and ۲۴% in PDAs that were, respectively, closed by medication, surgery, occlusion device and VATS in the first six months after the intervention. The percentages were, respectively, ۹%, ۱۰%, ۱۱% and ۹% for the second ۶ months after the intervention. The percentages were, respectively, ۲۴%, ۲۴% and ۲۱% in those PDAs with residuals, no complication and PH in the first six months after the intervention. This pattern was, respectively, ۸%, ۹% and ۱۶.۶% for the second ۶ months after the intervention.Conclusion: It was concluded that LA/AO ratio had the highest decrease during the first six months after the intervention, so that PDAs with moderate sizes or those who had medication as intervention or those with residual complications had the highest percentages of reduction.

Keywords:

LA/AO ratio , PDA , Closure , Children