Jitendra Gujar - Department of Chemistry, Karmaveer Bhaurao Patil Mahavidyalaya,(Autonomous) Pandharpur, Solapur (MS), INDIA.
Balaji Londhe - Department of Chemistry, Karmaveer Bhaurao Patil Mahavidyalaya,(Autonomous) Pandharpur, Solapur (MS), INDIA.
Raghunath Zambare - Department of Chemistry, Karmaveer Bhaurao Patil Mahavidyalaya,(Autonomous) Pandharpur, Solapur (MS), INDIA.
Rajesh Kavade - Department of Chemistry, Karmaveer Bhaurao Patil Mahavidyalaya,(Autonomous) Pandharpur, Solapur (MS), INDIA.
Murlidhar Shingare - Department of Chemistry, Dr. B. A. M.U., Aurangabad (MS), INDIA.

A single-pot, tandem reaction in which cyclization through condensation of ۱, ۲-diphenylethane-۱, ۲-dione, benzaldehyde, aniline, and ammonium acetate has been accomplished by orthodox condition. The reaction has been conducting in an aqueous medium with help of glycine. This compact purveys corresponding tetra-substituted imidazole derivatives in high yields, shorter duration of reaction, and simple work-up procedures with the green facets by eschewing harmful reagents.

Multicomponent reactions, tetra-substituted imidazoles, greener route, aqueous condition