Antifungal Effect of hexane extract of Euphorbia helioscopia root smoke

Candida albicans is one of the most commonly identified fungi in wounds and can be a cause of delayed wound healing. Since Euphorbia helioscopia root smoke is used traditionally to treat wound healing in west of Iran, we undertook the study to investigate antifungal properties of hexane extract of its root smoke against C. albicans ATCC ۱۰۲۳۱. Liquefied smoke of E. helioscopia root was extracted by hexane and its antifungal property was investigated using agar dilution method (۱, ۲, ۴, ۸, ۱۶, ۳۲, ۶۴, ۱۲۸ and ۲۵۶ mg/ml) on Sabouraud dextrose agar. Results showed that all concentrations of hexane extract of E. helioscopia root smoke inhibits C. albicans growth. Our study showed antifungal effects of the extract against C. albicans and demonstrated the accuracy of traditional use of E. helioscopia root smoke for treatment of wounds.

Keywords:

Antifungal , Candida albicans , Euphorbia helioscopia , hexane extract , wound.