Mehdi Shahabinejad - Oral and Maxillofacial Pathology Department, Oral and Maxillofacial Diseases Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Nooshin Mohtasham - Oral and Maxillofacial Pathology Department, Oral and Maxillofacial Diseases Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Farnaz Mohajertehran - Oral and Maxillofacial Pathology Department, Oral and Maxillofacial Diseases Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Maryam Mohammadi - Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Central Giant Cell Granuloma (CGCG) is a benign, intraosseous osteolytic lesion which often affects the mandible and its’ pathophysiology is not fully understood. Histopathology is still the dominant diagnostic method for this disorder. Clinically invasive lesions can lead to premature injury and may require invasive treatment to prevent recurrence .more than ۶۰% of all cases occur before the age of ۳۰. In spite of the fact that the sex ratio varies in different studies, giant cell granuloma is most commonly reported in women; and approximately ۷۰% occur in the mandible. Radiographically, giant cell granuloma is defined as radiolucent defects that may be uni-locular or multi-locular, which have an indefinite margin Most lesions are found in the anterior part of the jaw, and mandibular lesions often cross the midline In this study, a case of invasive CGCG of maxillary bone in a ۹-year-old boy with diagnostic and therapeutic challenges was presented.

CGCG, Osteolytic lesions, Maxillry bone, Pediatric patient