DFT/NBO A nalysis of Complexes between Nanotube s and Anti-HIV Dru gs

One of the efficient drugs tha t has anti H IV properties, is (+)/(- ) enantiomers of ۲ -deo xy-۳ - oxa-۴ -thiocytidine (dotc) or Apricitabine (AVX۷۵۴) . The most common side effects of this drug a re headache , nasal, congestion and muscle pain . Scientists have expressed their hope to de velop the use of carbon Nanotubes to release drugs ,… . It is very important to r elease drug in cell without damagi ng healthy cells of tissue under study. It is one application of Nanotubes. To pr event of drug’s side effects in use, in this w ork the interaction bet ween Nanotubes and this anti-HIV drug is investigated to s how if the Nanotubes a re safe to deliver this drug.

Keywords:

Nano tube , Thermodynamic Function , DFT , HIV