A systematic review of the patient-reported outcome measures (PROMs) of disability used for breast cancer survivors: ICF-based content validity and psychometric properties based on COSMIN criteria

Introduction & Aim: To identify currently used patient-reported outcome measures (PROMs) to evaluate disability in breast cancer survivors (BC) and critically evaluate their content and measurement properties. Methods: Four electronic databases (PubMed, EMBASE, CINAHL, Scopus and Google Scholar) were searched from ۲۰۰۱ to February ۲۰۲۱. PRISMA guidelines were followed. The content of the included PROM was evaluated by linking the items of the questionnaires to the International Classification of Functioning, Disability and Health (ICF) Core Set for BC using standard linking rules.Methodological quality and measurement properties were assessed using the COSMIN checklist.Qualitative synthesis was used to summarize the evidence on content validity and measurement properties. The overall quality of evidence on each measurement property was provided using GRADE principles. Results: Ten eligible studies reported measurement properties of seven PROMs. The content of included PROMs mostly focused on disability (۷۰% of items), and less on body function and structure (۲۳%) or environmental factors (۶%). There was high linkage to The Comprehensive Core Set for BC, Q-DASH (۱۰۰%), UEFI (۹۵%) and DASH (۹۲%). The Core Set Unique Disability Representation for DASH, and WHODAS۲ was ۳۹% and BSCQ-BC, Lymph-ICF was ۳۴%. BSCQ-BC, and Lymph-ICF represented ۳۲%, and ۲۰% of the content of the Core Set for BC, respectively. High quality of evidence supports sufficient results for internal consistency, test-retest, and measurement error for BSCQ-BC, Lymph-ICF, DASH and WHODAS۲. Conclusion: The content of BCSQ-BC, Lymph-ICF were more representative of the ICF core set for BC which are recommended to evaluate functioning and health in patients with BC.

Keywords:

Breast cancer survivors , Patient reported outcomes , Psychometric properties , Lymph-ICF , upper extremity , ICF core set for breast cancer , COSMIN