The use of radiotherapy during surgery in the treatment of brain tumors (systematic review)

Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_IJCA-1-4_006

تاریخ نمایه سازی: 24 بهمن 1400

Abstract:

Background: Brain tumors are less common than other cancers; however, they are associated with serious symptoms and poor prognosis.Most brain tumors are treated through surgery combined with radiotherapy and chemotherapy. These therapeutic methods are associated with neurotoxic complications and decrease the quality of life of patients. Intraoperative Radiation Therapy (IORT) is an innovative combination of surgery and radiotherapy, in which the direct radiation to the tumor bed during tumor resection is done. IORT is a new therapeutic method; therefore, the present ۵-year systematic review was conducted to introduce IORT and its advantages and disadvantages in the treatment of brain tumors. Methods: In this systematic review study, PubMed, Google Scholar, Cochrane Database, and Trip Medical Database, and CINAHL Database were searched for the published articles over a five year (۲۰۱۴ to ۲۰۱۹) using the keywords, including IORT and Brain Tumor and Intraoperative Radiation Therapy AND Brain Tumor. Articles were checked with the PRISMA checklist. Finally, ۵۰ articles were included in the study. Results: IORT method has been used in the treatment of brain tumors, especially glioblastoma. The effective radiation dose to treat brain tumors is ۱۵-۴۰ Gy. However, the appropriate technique and patient selection is the key to success with IORT. It is also used to treat recurrent pelvic, head and neck, and colorectal cancers, but it has shown more effective to treat brain tumors. Conclusion: IORT is an effective treatment for brain tumors, especially glioblastoma. It is more effective than external radiation therapy, due to the reduced tumor recurrence, maximal protection of healthy tissue, shorter duration of treatment, and cost-effectiveness.    

Authors

نیما عباسی ولدانی

Arak University of Medical Sciences

یاسمن پوراندیش

Arak University of Medical Sciences

فاطمه مهرابی

Arak University of Medical Sciences

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  • World Health Organization. Global Health Observatory. Geneva: World Health Organization; ...
  • Bray, F. et al. Global cancer statistics ۲۰۱۸: GLOBOCAN estimates ...
  • Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, ...
  • Ohgaki H, Kleihues P. Population-based studies on incidence, survivalrates, and ...
  • Ge L, Hoa NT, Cornforth AN, Bota DA, Mai A, ...
  • Arita H, Kinoshita M, Kagawa N, Fujimoto Y, Kishima H, ...
  • Ohgaki H, Kleihues P. Population-based studies on incidence, survivalrates, and ...
  • Kirkbride P, Tannock IF. Trials in palli-ative treatment-have the goal ...
  • Nimsky C, von Keller B, Schlaffer S, Kuhnt D, Weigel ...
  • Paulus W, Peiffer J. Intratumoral histologic heterogeneity of gliomas. A ...
  • Pötzi C, Becherer A, Marosi C, Karanikas G, Szabo M, ...
  • Preusser M, de Ribaupierre S, Wöhrer A, Erridge SC, Hegi ...
  • pakpour haji agha A, yekani nejhad M S, khoshnevisan A, ...
  • Citrin, D. E. Recent developments in radiotherapy. N. Engl. J. ...
  • De Ruysscher D, Niedermann G, Burnet NG, Siva S, Lee ...
  • Lee, A. W. et al. A multicenter, phase ۳, randomized ...
  • Baghani HR, Aghamiri SM, Mahdavi SR, Akbari ME, Mirzaei HR. ...
  • Cella L, Liuzzi R, Salvatore M. The Italian affair: the ...
  • Medina, Rosa, Francesc Casas, and Felipe A. Calvo. "Radiation oncology ...
  • Krengli, Marco, Felix Sedlmayer, Felipe A. Calvo, Elena Sperk, Carla ...
  • Matsumine A, Tsujii M, Nakamura T, Asanuma K, Matsubara T, ...
  • Nevelsky A, Bernstein Z, Bar‐Deroma R, Kuten A, Orion I. ...
  • Woolf DK, Williams NR, Bakshi R, Madani SY, Eaton DJ, ...
  • Bhandari T, Babaran W, Forouzannia A, Williams V, Harness J, ...
  • Mourtada F. Physics of intraoperative radiotherapy for the breast. Short ...
  • Patel R, Ivanov O, Voigt J. Lifetime cost-effectiveness analysis of ...
  • Mosalanezhad H, Kavosi Z, Keshavarz K, Akrami M, Sarikhani M. ...
  • Azzam AZ, Alqarni A, Amin TM. The role of intraoperative ...
  • Herranz E, Herraiz J, Cal-González J, Corzo P, Guerra P, ...
  • Esposito A, Sakellaris T, Limede P, Costa F, Cunha LT, ...
  • Falco M, Masojć B, Milchert-Leszczyńska M, Kram A. Frequency of ...
  • Willett, Christopher G., Brian G. Czito, and Douglas S. Tyler. ...
  • Harrison LB, Minsky BD, Enker WE, Mychalczak B, Guillem J, ...
  • ۳۴.Willett CG. Intraoperative radiation therapy. International journal of clinical oncology. ...
  • Calvo F, Sole C, Herranz R, Lopez-Bote M, Pascau J, ...
  • Gunderson LL, Willett CG, Calvo FA, Harrison LB. Intraoperative irradiation: ...
  • Biggs P, Willett CG, Rutten H, Ciocca M, Gunderson LL, ...
  • hosseini aghdam M R, baghani H, mahdavi S R, aghamiri ...
  • Nevelsky A, Bernstein Z, Bar‐Deroma R, Kuten A, Orion I. ...
  • Giordano FA, Brehmer S, Abo-Madyan Y, Welzel G, Sperk E, ...
  • Cifarelli CP, Brehmer S, Vargo JA, Hack JD, Kahl KH, ...
  • Cifarelli C, Hack J, Jacobson GM, Vargo JA. Feasibility of ...
  • Haneder, Stefan & Giordano, Frank & Konstandin, Simon & Brehmer, ...
  • Seddighi A, Esmaeil Akbari M, Seddighi AS, Rakhsha A, Vaezi ...
  • Giordano FA, Brehmer S, Mürle B, Welzel G, Sperk E, ...
  • Herskind C, Wenz F and Giordano FA. Immunotherapy Combined with ...
  • Pilar A, Gupta M, Ghosh Laskar S, Laskar S. Intraoperative ...
  • Kraus-Tiefenbacher U, Bauer L, Scheda A, Schoeber C, Schaefer J, ...
  • نمایش کامل مراجع