Husham - Faculty of Computer Science and Information Technology, Universiti Tun Hussein Onn Malaysia, Parit Raja ۸۶۴۰۰, Johor, Malaysia.
Mustapha - Faculty of Computer Science and Information Technology, Universiti Tun Hussein Onn Malaysia, Parit Raja ۸۶۴۰۰, Johor, Malaysia.
Mostafa - Faculty of Computer Science and Information Technology, Universiti Tun Hussein Onn Malaysia, Parit Raja ۸۶۴۰۰, Johor, Malaysia.
Al-Obaidi - Faculty of Electrical and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, Parit Raja ۸۶۴۰۰, Johor, Malaysia.
Mohammed - College of Computer Science and Information Technology, University of Anbar, ۱۱ Ramadi, ۵۵ Anbar, Iraq.
Abdulmaged - Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn Malaysia, Pagoh ۸۴۶۰۰, Johor, Malaysia.
George - Department of Biomedical Engineering, Karunya Institute of Technology and Sciences, Coimbatore ۶۴۱۱۱۴, India.

The accuracy of brain tumor detection and segmentation are greatly affected by tumors’ location, shape, and image properties. In some situations, brain tumor detection and segmentation processes are greatly complicated and far from being completely resolved. The accuracy of the segmentation process significantly influences the diagnosis process, such as abnormal tissue detection, disease classification, and assessment. However, medical images, in particular, the Magnetic Resonance Imaging (MRI), often include undesirable artefacts such as noise, density inhomogeneity, and partial volume effects. Although many segmentation methods have been proposed, the accuracy of the segmentation results can be further improved. Subsequently, this study attempts to provide very important properties about the size, initial location and shape of tumors known as Region of Interest (RoI) to kick-start the segmentation process. The MRI consists of a sequence of images (MRI slices) of a particular person and not one image. Our method chooses the best image among them based on the tumor size, initial location and shape to avoid the partial volume effects. The selected algorithms to test our method are Active Contour and Otsu Thresholding algorithms. Several experiments are conducted in this research using the BRATS standard dataset that consist of ۱۰۰ samples. These experiments comprised of MRI slices of ۶۵ patients. The proposed method is evaluated by the similarity coefficient as a standard measure using Dice, Jaccard, and BF scores. The results revealed that the Active Contour algorithm has higher segmentation accuracy when tested across the three different similarity coefficients. Moreover, the achieved results of the two algorithms verify the ability of the proposed method to choose the best RoIs of the MRI samples.

Brain tumor, Magnetic Resonance Imaging (MRI), Segmentation, Active contour, Otsu threshold