D. Gholami - Department of Bioprocess Engineering, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran
S. Aminzadeh - Department of Bioprocess Engineering, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran
S. M. Alavi - Department of Bioprocess Engineering, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran
N. Kazemipour - School of Veterinary Medicine, Shiraz University, Shiraz, Iran
A. Ghoroghi - Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research Education and Extension Organization (AREEO), P.O. Box: ۱۴۹۶۵/۱۴۹. Tehran, Iran.
Z. Emruzi - Department of Bioprocess Engineering, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran

Citrus canker is a citrus disease species created by the bacterium Xanthomonas citri subsp.citri. Many citrus, such as oranges, lime, and grapefruit are affected by the infectious bacteria and stems, leaves and fruits are experiencing loss. In this experiment antibacterial effects of five kinds of antibiotics including ampicillin, kanamycin, chloramphenicol, penicillin, streptomycin, Cronobacteriocin DGH۲ and Enterobacteriocin DGH۴ were evaluated on ۱۰۷ strains of Xanthomonascitri subsp.citri. MIC and MBC data for antibiotics and bacteriocins against Xanthomonas strains were performed. According to this project, Xanthomonas strains were comparatively susceptible and resistant to Cronobacteriocin DGH۲, Enterobacteriocin DGH۴, ampicillin, kanamycin, chloramphenicol, penicillin and streptomycin. NIGEB-۱۸۳ strain is the most sensitive to these antibiotics and bacteriocins. However, only the NIGEB-۲۴۲R۱ strain is resistant to chloramphenicol. Penicillin has minimum inhibitory effects on Xanthomonas strains. Based on this case study, chloramphenicol is the most antibacterial activity among antibacterial agents and this compound is a good candidate for inhibitory activity. Cronobacteriocin DGH۲ has a moderate antibacterial activity against Xanthomonas strains.

Antibiotics, Bacteriocins, Citrus canker, MIC and MBC data, Xanthomonas citri subsp.citri