Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditions
Publish place: Jorjani Biomedicine Journal، Vol: 6، Issue: 4
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JOBJ-6-4_008
تاریخ نمایه سازی: 14 اسفند 1400
Abstract:
Background and objectives: Today, due to the increasing antibiotic resistance of bacteria, the use of medicinal plants as a suitable alternative to antibiotics has increased significantly; therefore, in this study, the antibacterial effects of methanolic extracts of Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa and Escherichia coli were evaluated.
Methods: In this laboratory research, after collecting plants and confirming its scientific name, extract of Glycyrrhiza glabra L. Root was prepared by Soxhlet extractor method at concentrations of ۲۰ mg / ml to ۴۰۰ mg / ml. Then the antimicrobial effects of this extract were investigated using Agar well diffusion and Dilution test methods.
Results: The results showed that the methanolic extracts of G.glabra L. in both Agar well diffusion and Dilution test methods had antibacterial effects on the tested bacteria. The highest effect was observed on S.aureus and the lowest effect was observed in P.aeruginosa.
Conclusion: According to the above results, it can be expected that the G.glabra L. extract can be used to treat bacterial infections and is a suitable alternative to commonly used chemical treatments for the treatment of infections.
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Authors
Abolfazl Jafari-Sales
Department of Microbiology School of Basic Sciences, Kazerun Branch, Islamic Azad University, Kazerun, Iran
Parisa Bolouri
Department of Field Crops, Faculty of Agricalture, Ataturk University, Erzurum, Turkey.
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