Mehran Homam - MD Associate professor of neurology Department of neurology, Mashhad Branch, Islamic Azad University, Mashhad, Iran

Epilepsy is a chronic disorder with enormous psychological and social consequences. It might affect patients in different age groups and also in different epileptic syndromes.Research on the title of quality of life in epilepsy is defined by a wide range of methodology, including both in terms of study design and instruments has been designed. in the general population Quality of life is better than in patients with epilepsy; it might be worse in patients with epilepsy than that in patients with other chronic conditions; and it might be similar to that of healthy persons if patients with epilepsy be well-controlled. one of the most relevant determinants of poor quality-of-life (QOL) scores is frequency of seizures, and co-existence of depression could worsen quality of life.The impact of surgical treatment affects the quality of life in epileptic patients, in all ages, in correlation with seizure control. The role of antiepileptic drugs is controversial. the most investigated domains of quality of life in epilepsy are in emotional status and cognition.It is clear that in many researches the evaluation of quality of life and psychosocial functioning in people with epilepsy have been showed. however, the lack of a standardized approach results in difficult conclusion. Still there is no unique platform to know what measures should be used, in which patients, and in which sub-populations. With further sensitive measures of quality of life, it seems no longer appropriate to consider seizure frequency alone.