Optimizing Status Epilepticus management during the COVID-۱۹ pandemic

Publish Year: 1400
نوع سند: مقاله کنفرانسی
زبان: English
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EPILEPSEMED18_030

تاریخ نمایه سازی: 16 اسفند 1400

Abstract:

Status Epilepticus (SE) can represent a neurological manifestation of SARS-CoV-۲ infection. It can occur before respiratory or systemic involvement of COVID-۱۹, although more frequently it occurs within the context of a clinically overt respiratory infection. The lack of prompt access to EEG recordings may lead to an underestimate of its incidence, particularly for Non-Convulsive Status Epilepticus.The etiology of SARS-CoV-۲-related SE remains mostly unknown. A direct role of SARS-CoV-۲ invasion in the CNS or the systemic inflammatory syndrome due to cytokine release has been proposed as possible explanations. However, the association between SE and COVID-۱۹ could be spurious, and there may be other underlying conditions causally and independently related to both SE and COVID-۱۹.In treating SE, physicians will be challenged by the need for ICU resources and ventilators in the era of the COVID-۱۹ pandemic. The optimal approach could be minimizing anesthesia and intensive care unit (ICU) admissions for SE, with proper exclusion of psychogenic nonepileptic status and consideration ASD-antiviral medication interactions. A multidisciplinary approach are required that will use creative solutions, non-sedating ASDs, and risk–benefit calculations to best management of SE in this resource-constrained time.

Authors

Asieh Mehramiri

Department of neurology, Faculty of medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran