Isolation and Characterization of Furanocoumarins from Golden Delicious Apple Seeds

Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
View: 101

This Paper With 9 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_JMCH-5-4_009

تاریخ نمایه سازی: 15 فروردین 1401

Abstract:

The isolation, characterization, and exploration of the pharmacological potentials of natural-obtained products are the starting steps in discovering new pharmaceutical scaffolds. Coumarin-based products attract much of the research concern as secondary metabolites due to their structural variety and various phytobiological activities. In this study, the seeds of Golden Delicious apple were extracted by four solvents of various polarities, including water, ethanol, chloroform, and ethyl ether. This process was accomplished by applying three extracting techniques: kinetic, ultrasound, and microwave-supported maceration. Each technique was performed in three fashions based on the sequence of solvents’ utilization. The resultant ۳۶ extracts were scanned for the presence of certain phytoconstituents, and based on the gathered results, one of the extracts was selected to isolate its content of coumarin-based products. The isolated products were purified via column chromatography and the results acquired from the TLC technique revealed the isolation of two coumarins. The chemical structures of these two products were identified by their scanning on FTIR, ۱H-NMR, ۱۳C-NMR spectroscopies. From the acquired outcomes and the gathered evidence from the literature, it was concluded that the isolated coumarin-based products belong to the furanocoumarin category and are chemically identified as ۲-isoprenylxanthotoxin and chloromethylisopimpinellin.

Authors

Ban Ali Ahmed

Department of Pharmacognosy, College of Pharmacy, University of Mosul, Ninavah-۴۱۰۰۲, Iraq

Yasser Fakri Mustafa

Department of Pharmaceutical Chemistry, College of Pharmacy, University of Mosul, Ninavah-۴۱۰۰۲, Iraq

Bassam Yahya Ibrahim

Department of Plant Protection, College of Agriculture and Forestry, University of Mosul, Ninavah-۴۱۰۰۲, Iraq.

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :