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Paper
Title

Direct Aperture Optimization for Intensity Modulated Radiation Therapy: Two Calibrated Metaheuristics and Liver Cancer Case Study

فصلنامه بین المللی مهندسی صنایع و تحقیقات تولید، دوره: 33، شماره: 2
Year: 1401
COI: JR_IJIEPR-33-2_004
Language: EnglishView: 64
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Authors

Ali Fallahi - Department of Industrial Engineering, Sharif University of Technology
Mehdi Mahnam - Department of Industrial and Systems Engineering , Isfahan University of Technology, ۸۴۱۵۶-۸۳۱۱۱Center for Optimization and Intelligent Decision Making in Healthcare Systems (COID-Health), Isfahan University of Technology, ۸۴۱۵۶-۸۳۱۱۱
Seyed Taghi Akhavan Niaki - Department of Industrial Engineering, Sharif University of Technology

Abstract:

Integrated treatment plan design for cancer patients has high importance in intensity modulated radiation therapy (IMRT). Direct aperture optimization (DAO) is one of the efficient approaches used in recent years to attain this goal. Considering a set of beam directions, DAO is an integrated approach to optimize the intensity and leaf position of apertures in each direction. In this paper, first, a mixed integer-nonlinear mathematical formulation for the DAO problem in IMRT treatment planning is presented. Regarding the complexity of the problem, two well-known metaheuristic algorithms, differential evolution (DE) and particle swarm optimization (PSO), are utilized to solve the model. The parameter calibration is performed with the Taguchi method for both algorithms. The performance of algorithms is evaluated by solving the model for ۱۰ real liver cancer cases. The analysis of results demonstrates that the PSO algorithm outperforms the DE algorithm. Some directions are discussed for future researches.  

Keywords:

Radiation therapy treatment planning , Intensity modulated radiation therapy , Direct aperture optimization , Particle swarm optimization , Differential evolution

Paper COI Code

This Paper COI Code is JR_IJIEPR-33-2_004. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1429146/

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Fallahi, Ali and Mahnam, Mehdi and Akhavan Niaki, Seyed Taghi,1401,Direct Aperture Optimization for Intensity Modulated Radiation Therapy: Two Calibrated Metaheuristics and Liver Cancer Case Study,https://civilica.com/doc/1429146

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Type of center: دانشگاه دولتی
Paper count: 14,802
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