A Review on Clinical Manifestation and Treatment Regimens of UTI in Diabetic Patients
Publish place: Iranian Journal of Medical Microbiology، Vol: 16، Issue: 2
Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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JR_IJMM-16-2_002
تاریخ نمایه سازی: 28 فروردین 1401
Abstract:
The pervasiveness of urinary tract infections (UTIs) with their clinical manifestations in patients with diabetes mellitus has escalated amidst the past decade or so, as myriad predisposing factors contribute to its occurrence. Although the causative agent of UTI is Escherichia coli, the etiopathogenesis can be traced back to glycosuria in the renal parenchymal region. This has precipitated pyelonephritis and renal complications, including cytopathic and altered metabolism. Furthermore, impaired immunity with scarce IL-۶, ۸ in urine, urinary retention, and dysfunctional voiding raise susceptibility towards uropathogens, mainly E. coli. Treatment for UTI with diabetes is based on symptoms and severity, urologic abnormalities, renal function, bladder infections, and metabolic alteration. The treatment process or regimens for patients with type ۲ diabetes with asymptomatic bacteriuria are very low or negligible. Adequate management with antibiotic regimens in symptomatic patients after critical diagnosis is crucial for prophylaxis and effective treatment.
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Authors
Puneet Kaur
Adesh Institute of Pharmacy and Biomedical Sciences, Bathinda, Punjab, India
Rohan Samir Kumar Sachan
Department of Microbiology, Lovely Professional University, Phagwara, Punjab, India
Arun Karnwal
Department of Microbiology, Lovely Professional University, Phagwara, Punjab, India
Inderpal Devgon
Department of Microbiology, Lovely Professional University, Phagwara, Punjab, India
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