Synthesis of a New Copoly ۱,۳,۴-Oxadiazole from Copoly Imine with Iodine and Study of Their Biological Activity

Synthesis of a new series of poly (N-substituted-maleimide-co-۲,۵- substituted-۱,۳.۴-oxadiazole) was carried out. The first step includes preparation of copoly imine by reaction of different aldehydes with copoly acid hydrazide (۱-۱۵). The second step indicated the reaction of copoly imine with iodine in the presence of K۲CO۳ to give poly (N-substituted-maleimide-co-۲,۵-substituted-۱,۳.۴-oxadiazole). All prepared compounds were characterized by softening points, FT-IR, and some of them by ۱H-NMR and TGA, and then their Biological application was studied and some of the physical properties.

Keywords:

copoly Schiff bases , Copoly ۱ , ۳.۴-oxadiazole , Biological activity