Advanced Nasopharyngeal Carcinoma with Generalized Lymphadenopathy Masquerade as Lymphoma

Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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JR_IJOTO-34-3_010

تاریخ نمایه سازی: 24 اردیبهشت 1401

Abstract:

Introduction:Nasopharyngeal carcinoma (NPC) is a nasopharyngeal epithelial neoplasm that has distinct aetiological, epidemiological and biological characteristics compared to other head and neck malignancies. Patients usually present late due to non-specific symptoms and deep location of the tumour in the nasopharynx.Case ReportWe would like to highlight a case of advanced NPC presenting with generalised lymphadenopathy, without the presence of an obvious nasopharyngeal mass that masqueraded as lymphoma in the initial stage.Conclusions:NPC may share clinical features with other sinonasal pathologies or other malignant lymphoproliferative disorders that lead to a delay in diagnosis. NPC should be one of the differential diagnoses for any cases presenting with cervical lymphadenopathy, especially in adult male patients originating from East or Southeast Asia. Early diagnosis and treatment are crucial because early-stage NPC has an excellent chemoradiotherapy response and high survival rate.

Authors

V Sha Kri Eh Dam

Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, University Sains Malaysia Health Campus, ۱۶۱۵۰ Kota Bharu, Kelantan, Malaysia.

Nasibah Mohamad

Department of Radiology, School of Medical Sciences, University Sains Malaysia, Health Campus, ۱۶۱۵۰ Kota Bharu, Kelantan, Malaysia.

Izyan Rifhana Muhamad

Department of Pathology, School of Medical Sciences, University Sains Malaysia, Health Campus, ۱۶۱۵۰ Kota Bharu, Kelantan, Malaysia.

Al Duais Saleh Abdul Kadir Saeed

Department of Pathology, School of Medical Sciences, University Sains Malaysia, Health Campus, ۱۶۱۵۰ Kota Bharu, Kelantan, Malaysia.

Wan Faiziah Wan Abdul Rahman

Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, ۱۶۱۵۰ Kota Bharu, Kelantan, Malaysia.

Faezahtul Arbaeyah Hussain

Department of Pathology, School of Medical Sciences, University Sains Malaysia, Health Campus, ۱۶۱۵۰ Kota Bharu, Kelantan, Malaysia.

Azlan Husin

Department of Internal Medicine, School of Medical Sciences, University Sains Malaysia, Health Campus, ۱۶۱۵۰ Kota Bharu, Kelantan, Malaysia.

Norhafiza Mat Lazim

Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, University Sains Malaysia Health Campus, ۱۶۱۵۰ Kota Bharu, Kelantan, Malaysia.

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