Application of Electroconductive Hydrogels in Bone Regeneration as a new era in biomedical science

Electroconductive hydrogels (EHs) are promising composite biomaterials of hydrogels and conductive electroactive polymers which integrating bionic physicochemical possessions of hydrogels, conductivity, electrochemistry, and electrical stimulation (ES) sensitivity of conductive electroactive polymers together. The biomedical field has progressively seen EHs’ application to emulating the biological and electrical properties of human tissues, acclaimed as one of the most operative biomaterials. Bone’s composite bioelectrochemical properties and the consistent stem cell differentiation influenced by electrical signal raise EHs’ application value in repairing and treating bone, cartilage, and skeletal muscle. Noteworthily, the latest orthopedic biological applications need wider information of EHs. Except for offering the organization and synthesis of EHs, this review summarizes the develop of EHs application to orthopedics in the past five years and deliberates the pertinent development propensity and challenge, aiming to provide a reference for EHs application direction and prospect in orthopedic therapy.

Keywords:

Electrocunductive , Hydrogel , Bone regeneration , biomedical science