Gastrointestinal Manifestations in Patients Infected with SARS-CoV-۲

Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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JR_IJMM-16-4_001

تاریخ نمایه سازی: 16 خرداد 1401

Abstract:

Coronavirus disease ۲۰۱۹, caused by severe acute respiratory syndrome coronavirus ۲, has recently become the number one problem affecting global health. Coronavirus disease ۲۰۱۹ is principally recognized by its respiratory manifestations; however, recent studies have shown an increasing number of patients with gastrointestinal complaints like diarrhea, nausea, vomiting, and abdominal discomfort. Severe acute respiratory syndrome coronavirus ۲ infects the gastrointestinal tract via the angiotensin-converting enzyme II receptor, expressed on the ileum and colon enterocytes. Usually, gastrointestinal symptoms manifest later than respiratory symptoms. Concern for fecal-oral transmission has been raised following the detection of severe acute respiratory syndrome coronavirus ۲ RNA in fecal samples for prolonged periods, even after respiratory clearance. In this review, we summarize the effects of severe acute respiratory syndrome coronavirus ۲ on the gastrointestinal system.

Keywords:

COVID-۱۹ , fecal-oral transmission , gastrointestinal system , liver , SARS-CoV-۲ , کووید-۱۹ , ویروس کرونا سارس ۲ , دستگاه گوارش , انقال مدفوعی – دهانی و کبد

Authors

Nasir Arefinia

Department of Bacteriology and Virology, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Zohreh-al-Sadat Ghoreshi

Department of Biochemistry, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran

Amir Hossein Alipour

Department of Bacteriology and Virology, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Hamid Reza Molaei

Department of Bacteriology and Virology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran

Mohammad Samie

Department of Bacteriology and Virology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran

Jamal Sarvari

Department of Bacteriology and Virology, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

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