Challenging Results on FDG PET/CT in a Patient with Uncontrolled Celiac Disease and small bowel adenocarcinoma
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JNMB-10-2_011
تاریخ نمایه سازی: 21 خرداد 1401
Abstract:
Celiac disease (CD) is a chronic immune-mediated enteropathy that is caused by both environmental (gluten) and genetic (human leukocyte antigen (HLA) and non-HLA genes) factors. Patients may be asymptomatic or exhibit atypical symptoms, necessitating a high index of suspicion for proper diagnosis.The evaluation of CD patients with ۱۸F-FDG PET/CT imaging can be difficult, owing to the fact that this disease is inflammatory in nature. Typical ۱۸F-FDG PET/CT gastrointestinal manifestations of celiac disease include increased multifocal or diffuse bowel uptake, whereas single short segmental uptake is rarely encountered; thus, awareness of this wide range of findings is important to guide physicians through proper management and outcome.We report a case of small intestine adenocarcinoma and known CD complaining of recent episodes of diarrhea and weight loss that had a suspicious small bowel wall thickening that corresponds to a short segmental hypermetabolic process on FDG PET/CT follow-up scan. The patient was then referred to the gastroenterology department and underwent a colonoscopy, a biopsy was taken that revealed CD and was negative for malignancy. Furthermore, ۶ months later the abovementioned segmental FDG activity was completely resolved without any treatment received at the given time.
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Authors
Ali Mohamedkhair
Department of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan
Akram Al-ibraheem
Department of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan
Ahmed Abdlkadir
Department of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan
Omar Jaber
Department of pathology, King Hussein Cancer Center, Amman, Jordan
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