N. Nejaddadgar - Department of Health Promotion and Education, School of Public Health, Ardabil University of Medical Sciences, Ardabil, Iran
M. Jafarzadeh - Department of Infectious Diseases, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
A. Ziapour - Social Development & Health Promotion Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
F. Rezaei - Health Education and Promotion Department, health deputy, Ministry of Health, Iran

Aims: COVID-۱۹ has harmed people's lives and efforts are being made to speed up vaccinations. The growing problem of vaccine uncertainty may affect the uptake of the COVID-۱۹ vaccine. The objectives of this study were to examine the determinants of COVID-۱۹ vaccine acceptance. Materials & Methods: From July ۳ to September ۲۵, ۲۰۲۱, we conducted a web-based, cross-sectional study among the citizens of Ardabil with a snowball sampling strategy under a highly restricted environment. A questionnaire was designed and filled out by ۷۶۸ participants through social media and email. Associations between COVID-۱۹ vaccine acceptance and determinants were explored using the chi-squared test. Key determinants that predict vaccine acceptance among respondents were modeled through logistic regression analysis. Findings: Of the ۹۳۲ survey invitees, ۷۶۸ responded to the questionnaire (response rate, ۸۲.۴%). The majority (۵۵.۲%) of the study participants were female. Of the ۷۶۸ respondents, ۴۸۶ (۶۳.۲%) showed interest to accept the COVID-۱۹ vaccine. Willingness to get the vaccine is relatively high among older age groups (۵۹.۴% among ۴۰+ year old), being married (۵۶.۹%), and city dwellers participants (۸۳.۰۹%). In multivariate model, respondents who were above ۴۰ years (OR: ۰.۷; ۹۵% CI:۰.۵-۰.۹۴), and married (OR: ۱.۴۳; ۹۵% CI: ۰.۹۷-۲.۰۹) were significantly associated with vaccine acceptance (p<۰.۰۵). Besides, people having trust in the health system and vaccine were most likely to accept the vaccine (OR: ۱.۲۶; ۹۵% CI: ۱.۰۱-۱.۵۶), and those having a higher perceived risk of acquiring infection were ۴.۸۳ times (OR: ۴.۸۳; ۹۵% CI: ۳.۷۸-۶.۱۷) higher odds of accepting the vaccine. Conclusion: Our study identified religious/personal beliefs and risk perceptions as the most important predictors that would be affecting COVID-۱۹ vaccine uptake.  

COVID-۱۹, vaccine, Cross-Sectional, Web-based