Potassium Citrate as a Preventive Treatment for Double-J Stent Encrustation: A Randomized Clinical Trial
Publish place: Translational Research in Urology، Vol: 4، Issue: 1
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
View: 180
This Paper With 6 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_TUMS-4-1_006
تاریخ نمایه سازی: 1 تیر 1401
Abstract:
Introduction: This research was conducted to assess whether prophylactic citrate potassium can reduce double-J stent encrustation in patients with urolithiasis.Methods: In the present study, ۷۰ patients with urolithiasis were randomly assigned to two groups control [۲۲ men; mean age ۴۳ (۳۳-۵۵)] and intervention [۲۵ men; mean age, ۴۱ (۳۷-۵۶)] after meeting inclusion criteria. Potassium citrate (۱۰ mEq Alithoral tablet) was administered three times a day from double-J stent insertion until removal in the intervention group. For the control group, no treatment was given. It was examined after removing the stent, and laboratory tests were performed in encrustation. Moreover, blood and urine were collected for assessing creatinine, crystalluria, and pyuria. Information concerning the duration of double-J stent placement, the composition of urinary stone (calcium oxalate or other), number of attack episodes, type of double-J stent (one way or other), and smoking habit were collected. Results: Three control group participants were excluded from the study due to missing follow-up. Patients of the two groups were matched for age, sex, duration of the double-J stent placement, and the number of attack episodes. There were significant differences in crystalluria and creatinine dosage between the two groups. Furthermore, double-J stent encrustation occurred in ۳ (۸.۸%) and ۱۱ (۳۴.۴%) patients of the intervention and control group, respectively, which showed a significant difference (P-value=۰.۰۱۲). Comparison between the intervention and control group revealed an odds ratio of ۱۸% (P-value=۰.۰۱۷) and ۱۵% (P-value=۰.۰۲۳) in the crude and adjusted model, respectively. Conclusion: Potassium citrate can significantly reduce double-J stent encrustation in patients with urolithiasis. Therefore, it is recommended that urologists consider citrate potassium as a preventive treatment for encrustation.
Keywords:
Authors
Ali Tavoosian
Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
Amirhossein Rahimnia
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Elham Tehranipour
Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
Alireza Khajavi
Student Research Committee, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Seyed Saeed Tamehri Zadeh
Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
Vahid Abedi Yarandi
Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :