Evaluation of response to I-۱۳۱ ablative therapy in patients with differentiated thyroid carcinoma: A five year retrospective study [Persian]

Publish Year: 1379
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_IRJNM-8-1_003

تاریخ نمایه سازی: 7 تیر 1401

Abstract:

Differentiated thyroid carcinomas usually show good uptake and response to I-۱۳۱ ablative treatment. In this study, ۹۰ patients following near total thyroidectomy who were referred to our institute for I-۱۳۱ therapy are retrospectively studied. The patients are divided in two groups. Group ۱ revealed complete ablation after one dose of I-۱۳۱. Group ۲ needed more than one dose of I-۱۳۱ for ablation. ۲۶ patients (۲۸.۹%) were Categorized in group ۱ and ۶۴ patients (۷۱.۱%) in group ۲ patients. Comparison between the two groups revealed the highest success rate (Ablation with one dose of I-۱۳۱) in male patients between ۳۰-۵۰ years of age, with mixed type of differentiated thyroid carcinoma without any evidence of local or distant metastasis.

Authors

Mohammad Eftekhari

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran

Behnam Hajian

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran

Armaghan Fard-Esfahani

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran

Mohsen Saghari

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran