Nano-Cerium Oxide/Aluminum Oxide as an Efficient Catalyst for the Synthesis of Xanthene Derivatives as Potential Antiviral and Anti-Inflammatory Agents

Xanthenes have been considered in medicine and biology. Their medicinal properties include antiviral, antibacterial, anti-inflammatory, and therapeutic photodynamic activities, as well as the antagonist for paralytic action. ۱,۸-Dioxo-octahydroxanthenes have synthesized good yields via a reaction of aldehydes and dimedone in the presence of  cerium oxide/aluminum oxide nano-catalyst as a catalyst. High efficiency, short time and reuseability of catalyst are the advantages of this method.

Keywords:

Multicomponent reactions (MCRs) , nano- cerium oxide/aluminum oxide , Xanthenes derivatives , One-pot synthesis , anti-inflammatory agents