Tri Prihambodo - Graduate School of Nutrition and Feed Science, Faculty of Animal Science, IPB University, Bogor ۱۶۶۸۰, Indonesia
Muhammad Sholikin - National Research and Innovation Agency of Indonesia, Jakarta ۱۰۳۴۰, Indonesia
Nahrowi Nahrowi - Department of Nutrition and Feed Technology, Faculty of Animal Science, IPB University, Bogor ۱۶۶۸۰, Indonesia
Irmanida Batubara - Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor ۱۶۶۸۰, Indonesia
Desianto Utomo - Charoen Pokphand Group Co., Ltd., Jakarta ۱۴۴۳۰, Indonesia
Anuraga Jayanegara - Department of Nutrition and Feed Technology, Faculty of Animal Science, IPB University, Bogor ۱۶۶۸۰, Indonesia

In this study, a meta-analysis was employed to evaluate the effects of dietary flavonoids on laying hens. A database of flavonoids was developed from published journal papers in which flavonoids were supplemented to laying hens at various doses and then monitored for production performance, egg quality, liver condition, and antioxidant enzyme profile. A total of ۲۲ journal papers were included in the database, and statistically analyzed using a mixed-model methodology in which random effects consisted of the different studies and fixed effects were the dosages of flavonoids. The model statistics were p-value and Akaike information criterion. The significance of an effect was assumed at P < ۰.۰۵. The results showed that dietary addition of flavonoids linearly decreased (P < ۰.۰۰۱) feed intake. The laying rate was not affected by the addition of flavonoids, while the FCR tended to linearly decrease (P < ۰.۱). The addition of flavonoids linearly reduced egg and yolk cholesterol (both at P < ۰.۰۰۱), and linearly increased egg mass (P < ۰.۰۰۱), egg strength (P < ۰.۰۵) and yolk color (P < ۰.۰۰۱). Further, a linear decreasing response was observed in the liver triglyceride, and cholesterol concentrations (both at P < ۰.۰۰۱) after flavonoid supplementation. Superoxide dismutase showed a quadratic response (P < ۰.۰۱) following the addition of flavonoids. In conclusion, dietary supplementation of flavonoids is able to favourably modulate production performance and egg quality of laying hens.

Laying hen, Flavonoid, feed intake, meta-analysis, Superoxide dismutase