Mostafa Dehghani - Cardiovascular Research Center, Shahid Rahimi Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran
Mehrdad Namdari - Department of Cardiology, School of Medicine AND Cardiovascular Research Center, Shahid Rahimi Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran
Mahmoud Rafieian-Kopaei - Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Iran
Babak Baharvand-Ahmadi - Department of Cardiology, School of Medicine AND Cardiovascular Research Center, Shahid Rahimi Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran
Yaser Mokhayeri - Department of Epidemiology, School of Medicine, AND Cardiovascular Research Center, Shahid Rahimi Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran
Parsa Namdari - Student of Medicine, University of Debrecen Medicine School, Debrecent, Hungary
Morteza Dehghani - Student of Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Mostafa Cheragi - Associate Professor, Department of Cardiology, School of Medicine Lorestan University of Medical Sciences Khorramabad.

BACKGROUND: It seems that the time of performing cardiac rehabilitation is important in determining the risk of cardiac complications in patients with myocardial infarction (MI). The present study aimed to investigate the effects of a home-based cardiac rehabilitation program (HCRP) conducted in either the morning or evening on cardiometabolic risk factors in phase IV (maintenance) MI patients.METHODS: In this randomized controlled clinical trial, ۸۰ patients with MI were divided into ۲ groups of intervention and control (۴۰ individuals per group). Patients in each group were categorized into morning and evening subgroups (۲۰ individuals per subgroup). The therapeutic regimen in the intervention group included HCRP, routine medications, and exercise and walking programs for ۸ weeks. Patients in the control group received routine treatments for ۸ weeks. Cardiovascular risk factors comprising of cardiac troponin I (cTnI), mean platelet volume (MPV), C-reactive protein (CRP), and cardiometabolic indicators including cholesterol (Cho), high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglyceride (TG), and the maximum rate of oxygen consumption (VO۲ max) were measured for all patients before and after the intervention.RESULTS: Our results showed significant reductions in Cho, TG, HDL, LDL, VO۲ max, CRP, and MPV (P < ۰.۰۵) in the group performing HCRP in the evening compared with the morning group.CONCLUSION: Performing HCRP in the evening, compared with morning, can be significantly more effective in improving the levels of cardiometabolic risk factors in patients with MI. Therefore, it is recommended that rehabilitation programs be implemented in these patients in evening shifts.

Sudden Cardiac Death, Cardiac Rehabilitation, Time, Myocardial Infarction, Risk Factors