Hamidreza Roohafza - Assistant Professor, Department of Mental Health, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Ali Kabir - Assistant Professor, Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran
Masoumeh Sadeghi - Professor, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Pedram Shokouh - PhD Fellow, Department of Endocrinology and Diabetes, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Masoud Ahmadzad-Asl - Assistant Professor, Mental Health Research Center, Tehran Institute of Psychiatry AND School of Behavioral Sciences and Mental Health, Iran University of Medical Sciences, Tehran, Iran
Ali Akbar Khadem-Maboudi - Associate Professor, Department of Biostatistics, School of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Nizal Sarrafzadegan - Professor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

BACKGROUND: We have assessed the role of stress on compliance of patients with diabetes mellitus (DM) and hypertension (HTN) with taking prescribed medications and following dietary and exercise regimens. METHODS: A total of ۹۵۴۴ individuals more than ۱۹ years of age were selected from three counties in central Iran. The presence of DM and HTN were asked from participants. We defined treatment adherence (compliance) based on agreement of individual’s self-report behavior with recommendations from a physician. RESULTS: Awareness about DM and HTN was ۸۲.۶% and ۴۹.۹%, respectively. Multivariate analysis showed that odds ratio (OR) of high to low stress level was lower than one for both “usage of medication” and “following exercise regimen” in diabetics even after adjustment for either “age and sex” or “age, sex and education”. In hypertensive patients, OR of high to low stress level was lower than one for “usage of medication” even after adjustment for either “age and sex” or “age, sex and education” and also lower than one for “following exercise regimen” only as crude index. CONCLUSION: Cases with higher stress level had lower compliance for accepting either medication or exercise as a treatment option for their DM or HTN. 

Stress, Patient Compliance, Risk Factors, Exercise, Diabetes Mellitus, Hypertension