GENE POLYMORPHISM AND HYPERTENSION
Publish place: ARYA Atherosclerosis، Vol: 8، Issue: 0
Publish Year: 1391
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_RYA-8-0_019
تاریخ نمایه سازی: 3 شهریور 1401
Abstract:
Hypertension is a significant health problem worldwide and affects more than ۲۰% of the adult population. This disorder has an important role in morbidity and mortality of heart and kidney disease patients. It is believed that essential hypertension is a multifactorial and polygenic disease; resulting from an interplay between environmental and genetic factors. In this paper, we will review studies that have inspected new genome screen and introduced a new viewpoint on candidate genes of essential hypertension. We discuss on polymorphism of candidate genes which related in the pathogenesis of hypertension and take from experimental models or knowledge of the pathophysiology. Study on genetic factors of hypertension may be developing new treatment for these patients.
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Authors
Heidar Tavilani
Associate Professor, Urology and Nephrology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
Maryam Esfahani
PhD Candidate, Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran