Oral Immunotherapy in Children: Ige-Dependent Food Allergy to Milk or Wheat
Publish place: International Journal of Pediatrics، Vol: 10، Issue: 8
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_INJPM-10-8_008
تاریخ نمایه سازی: 13 شهریور 1401
Abstract:
Oral Immunotherapy (OIT) is an effective strategy for improving food allergy tolerance. OIT has been introduced as a novel immune-modulating medication for food allergies. Other immunomodulatory approaches, such as sublingual (SLIT) or epicutaneous (EPIT) immunotherapy, may be less effective due to lower frequencies of systemic responses. Wheat and milk have lately been identified as a more prevalent cause of food-induced anaphylaxis than previously thought, particularly in young children worldwide. An immunoglobulin E (IgE)-dependent pathway may be responsible for wheat or milk allergy. The goal of our study was to offer a comprehensive evaluation of the effects of OIT in children with IGE-dependent food allergies to milk or wheat. Keywords related to OIT, food allergy, milk, wheat, and children were searched in MEDLINE, PubMed, Google Scholar, and ScienceDirect databases. Although oral immunotherapy for wheat allergy has recently been proposed, research studies have had encouraging results; despite, more research is still needed to determine the optimum strategy for promoting tolerance in wheat/milk-allergic children
Keywords:
Oral immunotherapy- food allergy- children-Milk , Wheat
Authors
Fasihe Mazandarani
Pediatric resident in Mashhad University of Medical Sciences
Hamid Ahanchian
Clinical Research Development Unit of Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Nasrin Moazzen
Clinical Research Development Unit of Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
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