Importance of IL-۱β in SARS-CoV-۲ infection

Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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JR_INJPM-10-9_015

تاریخ نمایه سازی: 2 مهر 1401

Abstract:

Severe acute respiratory syndrome coronavirus ۲ (SARS-CoV-۲) provokes the host immune responses and induces severe respiratory syndrome by overreaction of immune cells. IL-۱β is a pro-inflammatory cytokine highly associated with the related inflammation and cytokine storm, and several IL-۱β antagonists are being used to treat cytokine release syndrome (CRS). Accordingly, some studies and clinical trials are investigating the effects of IL-۱β antagonists for controlling Coronavirus disease ۲۰۱۹ (COVID-۱۹) associated CRS. Here, we will review any interaction and association between IL-۱β and SARS-CoV-۲ infection.

Authors

Emad Behboudi

Golestan University of Medical Sciences

Hossein Teimouri

Golestan University of Medical Sciences

Vahideh Hamidi-Sofiani

Department of Microbiology, Golestan University of Medical Sciences, Gorgan, Iran.

Ali Memarian

Golestan University of Medical Sciences

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