Mahla Sheikhveisi - Department of Chemistry Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, Iran
Nourallah Hazeri - Department of Chemistry Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, Iran
Mojtaba Lashkari - Department of Chemistry Faculty of Sciences, University of Velayat, Iranshahr, Iran
Homayoun FaroughiNiya - Department of Chemistry Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, Iran
Maryam Fatahpour - Department of Chemistry Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, Iran

Pseudo-three-component synthesis of N,N'-diaryl-۲-aryl-۶-hydroxy-۶-methyl-۴-oxocyclohexane-۱,۳-dicarboxamide derivatives (۳a-g) was performed by the reaction of acetoacetanilide and aromatic andaliphatic aldehydes with ۴-(dimethylamino)pyridine (DMAP) as a base catalyst. This reaction proceededgently in a reaction vessel at ۸۰ °C under solvent-free conditions. Among the index features introduced inthis research, we can mention the short reaction time, simple and easy separation and purification of productswithout the use of chromatographic columns in the synthesis of this group of highly substitutecyclohexanones.

۴-(Dimethylamino)pyridine (DMAP) catalyst, Pseudo-three-component, Highly substitutedcyclohexanone