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Association of Serum Anti-Heat Shock Protein ۲۷ Antibody with Obesity Risk among Healthy Individuals in MASHAD Study

عنوان مقاله: Association of Serum Anti-Heat Shock Protein ۲۷ Antibody with Obesity Risk among Healthy Individuals in MASHAD Study
شناسه ملی مقاله: JR_JCTM-10-3_002
منتشر شده در در سال 1401
مشخصات نویسندگان مقاله:

Fatemeh Sadabadi - Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Zahra Asadi - Metabolic Syndrome Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Alireza Heidari Bakavoli - Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Susan Darroudi - International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Maryam Saberi-Karimian - International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Saniya Saljoughian - Metabolic Syndrome Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Maryam Shahi - Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Mashhad, Iran.
Mohammad Safarian - Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohsen Nematy - Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Gordon A. Ferns - Department of Medical Education, Brighton & Sussex Medical School, Brighton, BN۱ ۹PH, UK.
Majid Ghayour-Mobarhan - Metabolic Syndrome Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohsen Mouhebati - Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

خلاصه مقاله:
Introduction: The association between the serum antibody titer of several heat shock proteins (HSPs) and cardiovascular disease (CVD) risk factors so far has been the subject of several previous studies.Aim: To evaluate the association of adiposity indices and HSP-۲۷ antibody titers in healthy individuals.Materials and Methods: Overall ۴۸۲۳ individuals were recruited from Mashhad Stroke and Heart Atherosclerotic Disorders Study (MASHAD study), that included ۱۴۹۶ individuals with normal-weight (body mass index (BMI) <۲۵ kg/m۲), ۱۹۷۵ individuals with over-weight (BMI ۲۵-۳۰ kg/m۲), and ۱۳۵۲ individuals with obesity (BMI≥ ۳۰ kg/m۲).Results: The serum anti-HSP-۲۷ antibody titers were not significantly different among obese individuals [۰.۲۱ (۰.۱۱ – ۰.۳۴) absorbency unit (AU)], over-weight individuals [۰.۱۹ (۰.۱۰ – ۰.۳۳) AU] and normal-weight individuals [۰.۱۹ (۰.۱۰ – ۰.۳۳) AU].Conclusions: we have found no significant relationship among anti-HSP-۲۷ antibody concentration and degrees of adiposity among Iranian adults.

کلمات کلیدی:
Cardiovascular Disease, Heat shock proteins, Obesity

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1528744/