Bita Baghernejad - Department of Chemistry, School of Sciences, Payame Noor University (PNU), ۱۹۳۹۵-۴۶۹۷, Tehran, Iran
Seyedeh Mozhgan Hojjati Taromsari - Department of Chemistry, School of Sciences, Payame Noor University (PNU), ۱۹۳۹۵-۴۶۹۷, Tehran, Iran

۲-amino-۴H-benzopyran derivatives have received considerable attention due to their valuable biological and medicinal properties such as anticoagulant, antispasmodic, diuretic, and anti-cancer activities. Benzopyran derivatives have strong relaxing activity on blood vessels, cardiac muscles, and smooth muscles. The present study reports the easy synthesis of ۴H-benzopyran derivatives by using aldehyde, malononitrile, and dimedone in the presence of cerium(IV) oxide nanopowder as a non-toxic catalyst. The advantages of this method include catalyst recovery, high efficiency, short reaction time, and ease of operation method.

۲, Amino, ۴H, benzopyran NanoCeO۲ One, pot Multi, component reaction