Arash Rahimi - نویسنده اول
Maede Ansari - نویسنده دوم
Parivash Davoodian - نویسنده سوم
Saeed Shoja - نویسنده چهارم
Saeed Hosseini Teshnizi - نویسنده پنجم
Hesam Alizade - نویسنده مسئول

Background: The present study attempted to determine the antibiotic susceptibility of bacteria isolated from endotracheal tube culture on patients admitted to the intensive care units (ICUs) of Shahid Mohammadi hospital in Bandar Abbas.Materials and Methods: This cross-sectional study was conducted on ۱۱۴ patients hospitalized in the pulmonary ICU of Shahid Mohammadi hospital in Bandar Abbas from March ۲۰۱۸ to March ۲۰۱۹. The samples of the patients’ endotracheal tube secretions were collected for the culture purpose on the first and fifth days of hospitalization in the ICU where the disk diffusion method was used to determine antibiotic susceptibility.Results: The most common isolated microorganisms from the first day of culture were ۲۶ Acinetobacter spp. isolates (۲۲.۸%), ۱۰ Candida isolates (۸.۸%), and ۹ Pseudomonas aeruginosa isolates (۷.۹%). The most common microorganisms which were isolated on the fifth day comprised Acinetobacter spp. with ۵۷ isolates (۵۱.۸%), Candida with ۶ isolates (۵.۵%), and P. aeruginosa with ۶ isolates (۵.۵%). The highest resistant bacteria isolated from Acinetobacter spp. samples on the first-day were amikacin (۹۲.۳%) and meropenem (۸۴.۶%). The highest resistance of P. aeruginosa was against meropenem (۷۷.۸%), while the highest resistance of Acinetobacter spp. isolates was found to be amikacin (۹۴.۷%) and meropenem (۸۶%) from the fifth-day samples. Further, P. aeruginosa isolates had the highest resistance in meropenem (۸۳.۳%), co-trimoxazole, and cefepime (۶۶.۷% for each of them).Conclusion: Ventilator-associated pneumonia (VAP) is considered a warning condition due to multi-drug-resistant bacteria. According to the present study, the most common VAP-causing bacteria are gram-negative, especially Acinetobacter, with high antibiotic resistance.

Ventilator-associated pneumonia, Endotracheal intubation, Antibiotic resistance, ICU