Effects of Black Cumin (Nigella sativa L.) on patients with cancer and tumor: A systematic Review

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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JR_JCBIOR-2-1_003

تاریخ نمایه سازی: 9 آبان 1401

Abstract:

Experimental studies demonstrated a positive effect of administration of Nigella sativa L. (Black cumin) and its active chemical components on cancer and tumor through the antioxidant and anti-cancer activity. This study aimed to determine the beneficial effect of the use of black cumin in patients with cancer and tumor. This systematic review includes ۴ randomized controlled trials that investigated the effect of the administration of black cumin in human cancer. Articles were searched in PubMed, Cochrane library, Semantic scholar and directory of open access journal (DOAJ), open grey and grey literature report databases for studies from ۱۹۸۳ to ۲۰۲۰ before May using the following keywords, Nigella sativa, black cumin, cancer, tumor, etc. The results examined that N. sativa is much effective in treating breast cancer, gastrointestinal cancer, brain tumor, and acute myeloid leukemia. According to the limited evidence from the study, black cumin may have favorable effects on cancer and tumor. However, more research is needed on different types of cancer to confirm and establish the above findings.

Authors

Mohammad Asadul Habib

Department of Food Technology and Nutrition Science, Noakhali Science and Technology University, Naokhali-۳۸۱۴, Bangladesh- Department of Nutrition, World Vision International, Cox’s Bazar, Bangladesh

Akibul Islam Chowdhury

Department of Food Technology and Nutrition Science, Noakhali Science and Technology University, Naokhali-۳۸۱۴, Bangladesh

Monia Afroze

Department of Food Technology and Nutrition Science, Noakhali Science and Technology University, Naokhali-۳۸۱۴, Bangladesh

Tanjina Rahman

Department of Food Technology and Nutrition Science, Noakhali Science and Technology University, Naokhali-۳۸۱۴, Bangladesh