Siamak Yaghoubi - Associate Professor, Department of Anesthesiology, Qazvin University of Medical Sciences, Qazvin,
Nilofar Massoudi - Assistant Professor, Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Hamid Kayalha - Associate Professor, Department of Anesthesiology, Qazvin University of Medical Sciences, Qazvin,
Karen Samimi - Resident of Anesthesia, Department of Anesthesiology, Qazvin University of Medical Sciences, Qazvin, Iran

Background: Post-intubation airway complications such as cough and sore throat are common complaints after anesthesia. After intubation, filling the endotracheal tube will close the tube space and stimulate the endotracheal tube. It is used to fill the cuff with air or liquids such as normal saline, lidocaine, etc. The purpose of this study was to compare the comfort of tracheal extubation between the two methods of filling the tracheal cuff with lidocaine ۲% and filling with air in patients undergoing laparoscopic cholecystectomy.Methods and materials: In this single-blind clinical trial study, ۷۰ patients were randomly divided into two groups of air and lidocaine. In the lidocaine group, the endotracheal tube cuff was filled with ۲% lidocaine and in the air cuff group the cuff pressure reached ۲۰ to ۲۵ cm of water. Blood pressure and heart rate of patients before induction, after induction, ۳۰ and ۶۰ minutes after and before and after extubation, as well as complications of intubation including bucking, cough and sore throat during recovery, ۶ hours and ۱۲ hours later were compared. Data were analyzed using SPSS software version ۱۶.Results: The results of this study showed that there were no significant differences in heart rate at different intervals of the study including pre-induction, post-induction, ۳۰ and ۶۰ min, before and after extubation. But the systolic and diastolic blood pressure after extubation were significantly lower in the lidocaine group than in the air group, although at other intervals there was a significant difference between the two parameters in the study groups. After extubation, sore throat complications were significantly lower at all study intervals.Conclusion: According to the results of the same study, it seems that filling the cuff with lidocaine over the air leads to more hemodynamic stability and less side effects after extubation.

Intubation, Lidocaine, Complications