Preparation and Characterization of New Hetrocyclic Azo Thiozal Dye Ligand and Its Use as a Reagent for Determination of Zn+۲ Ion in Drug by New Analytical Method

A novel heterocyclic organic ligand was synthesized by using a novel azo reagent and characterized by the organic diagnostic methods such as FT-IR, ۱H-NMR, and UV-Vis. The novel azo reagent was employed in the analytical approach to find trace levels of zinc(II) ion in several drug models. The complex was formed after studying the optimal conditions for its synthesis in a reagent: zn+۲ ratio of ۱:۱. The largest absorption peak was seen at ۶۲۰ nm in wavelength. In contrast, the reagent wavelength was ۴۷۵ nm. The linear range was between concentration and absorption at longer wavelength ranges ۰.۳ - ۲۰ mg/L. The approach has an accuracy of percent RSD ۰.۹۲۵۹ and SD =۰.۰۰۰۵. Sandal sensitivity, LOD, and LOQ are each ۰.۲۶۳۲, ۰.۸۷۷۲ g/mL, and ۰.۱۷۵۴ g.cm-۲, respectively. The impact of various positive and negative ions on complex absorption was examined to demonstrate the method's selectivity. Under the optimal pH ۶.۵ to ۷ conditions and an absorption temperature of ۲۵ to ۴۰ °C, the percentage recovery of the drug by the suggested method varied from ۹۵ to ۱۰۴ %.