Triphenylphosphine promoted one-pot synthesis of alkyl (Z)-۲-((Z)-۲-(alkylimino)-۴-oxo-۳-phenylthiazolidin-۵-ylidene)acetate derivatives from the reaction of N-phenylthiourea derivatives and dialkyl acetylenedicarboxylates

Publish Year: 1401
نوع سند: مقاله کنفرانسی
زبان: English
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تاریخ نمایه سازی: 19 آذر 1401


The reaction of N-phenylthiourea derivatives with dialkyl acetylenedicarboxylates in thepresence of triphenylphosphine leads to synthesis of alkyl (Z)-۲-((Z)-۲-(alkylimino)-۴-oxo-۳-phenylthiazolidin-۵-ylidene)acetate derivatives in excellent yields. These compounds also biologicalinteresting. All products were established by IR, ۱H, ۱۳CNMR, Mass spectroscopy and elementalanalysis.


Milad Bazaz Rastkar

Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran