Mohammad Hasanpour - Mohammad Hasanpour , Assistant professor , Department of neurosurgery, Iran university of medical science.
Sayedeh Sadatmadani - Medical Doctor, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Bahar Sadeghi - Medical Doctor, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Azar Baradaran - Professor of Pathology, Infectious Diseases and Tropical Medicine Research Center, Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran
Vahid Mansouri - Medical Doctor, Digestive disease research institute, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran
Ehsan keykhosravi - Department of neurosurgery,faculty of medicine , Mashhad university of medical sciences , Mashhad ,Iran

Case Report: A ۲-year-old girl was referred with the chief complaint of limb weakness following a mild trauma. She had been suffering from restlessness and neck pain for a month. Laboratory findings were normal. In MRI, there was evidence of craniocervical junction extra-axial mass lesion arising from the posterior aspect of the dense process ligamentous complex extending from the foramen magnum to the posterior fossa with engulfment of the right vertebral artery. Regarding the compressive effect of the tumor, a right trans-condylar suboccipital surgical approach was used to resection the mass, near totally, and decompress the brain stem. Immune-Histo-Chemical Staining (IHC) showed a grade ۲ meningioma. Low-dose radiotherapy was applied; but the pathology result corroborated the tumor’s radiologic features. Due to the follow-up MRI evidence of aggressive tumor recurrence the clinical behavior of the tumor and the patient's progression, there was a possibility that the first diagnosis was not correct; hence, a second operation was performed during which a smaller portion of the tumor could be resected compared with the first operation. Pathological study and IHC staining reported MRT and tumor markers, including pan-cytokeratin (CK), epithelial membrane antigen (EMA), and vimentin, were strongly positive. So, a chemotherapy regimen was added to radiotherapy. Unfortunately, the patient did not respond well to the follow-up treatment, and she expired after one year. Conclusion: In similar cases, where the radiological and pathological features of the tumor are atypical, the histological examination should include molecular examination, as meningioma in this age group is extremely rare. And, confirming the pathological and molecular characteristics of the tumor by different experts is strongly recommended.

Rhabdoid tumor,,, ,،malignant rhabdoid tumor,,, ,،atypical teratoid/rhabdoid tumor,,, ,،craniocervical junction tumor,,, ,،meningioma