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Synthesis, Characterization and Study Biological Activity of Some ۱,۲,۴-Triazin Heterocyclic Derivatives

عنوان مقاله: Synthesis, Characterization and Study Biological Activity of Some ۱,۲,۴-Triazin Heterocyclic Derivatives
شناسه ملی مقاله: JR_JMCH-6-7_006
منتشر شده در در سال 1402
مشخصات نویسندگان مقاله:

Safaa Thamer Ahmed - Department of Chemistry, College of Science, University of Babylon, Iraq
Shireen R. Rasool - Department of Chemistry, College of Science, University of Babylon, Iraq

خلاصه مقاله:
A series of some new heterocyclic compounds containing triazin derivatives have been synthesized in many steps sequence. Triazine derivatives were prepared through reacting benzil with semicarbazide or thiosemicarbazide to form ۵,۶-diphenyl-۱,۲,۴-triazin-۲(۳H)one,۵,۶-diphenyl-۱,۲,۴-triazine-۲(۳H)thione, respectively. A hydroxymethylation reaction has been made to the amide group. The hydroxyl group was replaced by azide group. A different substituted triazine rings have been formed using different reagents. The structures of the newly prepared derivatives were identified through more than one technique like (FT-IR, ۱H-NMR, and ۱۳C-NMR) for all derivatives.

کلمات کلیدی:
Heterocyclic compounds, Benzyl, triazine derivatives, Quinazoline, Triazole, tetrazole, Amidazoldine

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1576101/